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ISSN: 2994-4295

Archive of Biochemistry

    Volume - 8 (1)
    mendeley

    Development of a High-throughput Assay to Identify Novel Reactivators of Acetylcholinesterase

    DOI Logo 10.17352/ab.000011

    Published On: September 20, 2025 | Pages: 001 - 008

    Author(s): Becky L Hood*, Stefan Vasile, Gideon Shapiro and James D Talton

    ORCID Logo  0009-0001-1865-5852

    Acetylcholinesterase (AChE) is a key enzyme in the nervous system capable of breaking down acetylcholine (ACh). ACh is a critical neurotransmitter that signals between nerve cells and muscles. Organophosphates (OPs), used as insecticides and nerve agents, irreversibly inhibit AChE by forming a covalent bond with the enzyme’s active site. Since exposure to these nerve ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Asuncion National University, Paraguay
    Global Journal of Medical and Clinical Case Reports
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    Queen Elizabeth Hospital, Hong Kong
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    Archive of Gerontology and Geriatrics Research
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    Oklahoma University, USA
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    Columbia University, USA
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    Southeastern University, China
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    Taipei Medical University, Taiwan
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    Tufts University, USA
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