Research Interest: Pharmaceutical organic chemistry and Pharmaceutical analytical chemistry; Development of chromatographic and immunoassay methods for analyzing different pharmaceutical compounds in biological fluids which could be used in bio-studies.  drug-drug interactions and drug-juice interaction and on the synthesis of some Barbituric acid and Imidazole derivatives and their application in pharmaceutical products. NMR, X-ray, LC/MS, HPLC and ELISA.

Research Interest: Allelopathy and allelopathic substances of medicinal plants, Biological activity of natural products, Herbicides development from natural products, Organic farming and Precision agriculture.

2017-Postdoctoral researcher

Gaziosmanpasa University, Turkey Plant Research Lab of Chemistry, Faculty of Arts and Sciences

2011-2016 PhD (Research Assis-tant) Gaziosmanpasa University Molecular Biology and Genetics, Faculty of Arts and Sciences

2008- 2011 Master (Research Assis-tant) Gaziosmanpasa University Molecular Biology and Genetics, Faculty of Arts and Sciences

2003-2007 Under graduate Cumhuriyet Univer-sity Biology, Faculty of Arts and Sciences

Research Interest:  Algae cultivation, Plant biotechnology, Secondary metabolite production

Grants: 

1. Bioprocessingof microalgae for production and recovery of high-value metabolites;", Texas A&M University, 23.08.2015 -29.11.2015

2. Activity Controlled Isolation of Isolated Secondary Metabolites from Cladophora fracta (Tubitak 2017-2018).

3. Investigation of Pharmacological Secondary Metabolites in Some Cyanobacteria Members and Investigation of the Effects of Various Stress Conditions on the Production of these Metabolites (2016- 2018 Bap Turkey).

List of Publications: 

1. Tunay Karan, Ramazan Erenler Zekeriya Altuner, Mahfuz Elmastas. Molecular Identification and Norharmane Quantification of Cyanobacterium, Geitlerinema carotinosum. International Journal of Pharmacy& Pharmaceutical Research.June 2017,  Vol.:9, Issue:3, 67-73.

2. Tunay Karan, Ramazan Erenler. Screening of Norharmane from Seven Cyanobacteria by High performance Liquid Chromatography. Pharmacogn. Mag. 11.10.2017, Vol: 13, Issue: 51, 723-725.

3.Tunay Karan, Zekeriya Altuner, Ramazan Erenler. Growth and Metabolite Production of Chroococcus minutus Under Different Temperature and Light Conditions. Journal of New Results in Science, 6:1 47-52, 2017.

4. Tunay KARAN, Taner DAŞTAN, İnanç BARAL, Zekeriya ALTUNER.   Effects of Differential Time Applications on Some Cyanobacterial Norharman Production Rates.  Cumhuriyet Üniversitesi Fen Fakültesi Fen Bilimleri Dergisi (CFD), Cilt 37, No. 4 (2016) ISSN: 1300-1949.

5. Tunay KARAN, Ramazan ERENLER, Zekeriya ALTUNER. Isolation and Molecular Identification of Some Blue-Green Algae (Cyanobacteria) from Freshwater Sites in Tokat Province of Turkey. Turkish Journal of Agriculture - Food Science and Technology, 5(11): 1371-1378, 2017

6.Tunay KARAN, Saban Tekin, Ahmet Bursalı, Adem Keskin. Investigation of Tick-Borne Encephalitis Virus (TBEV) in Ixodid Ticks  Collected from Central Black Sea Region in Turkey. Journal of New Results in Science 4 (2014) 30-35

7.Sevgi Durna Dastan, Naci Degerli, Taner Dastan, Fazilet Yildiz, Yavuz Yildir, Yusuf Muhammed Durna, Dilek Atessahin  and Tunay Karan. Phenylthiocarbamide taste perception as a possible genetic association marker for nutritional habits and obesity tendency of people. Pak. J. Pharm. Sci., Vol.28, No.3(Suppl), May 2015, pp.1141-1150. 

8. Sevgi Durna Daştan, Taner Daştan, Serap Çetinkaya, Dilek Ateşşahin, Tünay Karan. Evaluation of In Vitro Anticancer Effect of Plantago major L. and Plantago lanceolata L. Leaf Extracts from Sivas. Cumhuriyet Üniv. Sağ. Bil. Enst. Derg. 2016 (1)1: 07-14

9. Tunay KARAN, İlyas Yıldız, Ali Aydın, ,Ramazn Erenler Inhibition of Various Cancer Cells Proliferation of Bornyl Acetate and Essential Oil from Inula graveolens (Linnaeus) Desf.  Rec. Nat. Prod. 12:3 (2018) 273-283

10. Ramazan Erenler, Tuğba Adak, Tunay KARAN, Mahfuz Elmastaş,İlyas Yıldız, Hüseyin Akşit,Gülaçtı Topcu,Murat Aydın Sanda. CHEMICAL CONSTITUENTS ISOLATED FROM ORİGANUM SOLYMICUM WITH ANTIOXIDANT ACTIVITITES. The Eurasia Proceedings of Science, Technology, Engineering & Mathematics (EPSTEM)  2017,Volume 1, Pages 139-145

11. Tünay KARAN, Mesut KOYUNCU, İskender PARMAKSIZ, Köksal PABUÇCU, Zekeriya ALTUNER. Siyanotoksinler ve Biyosentezlerinden Sorumlu Genlerin Düzenlenmesi. Gaziosmanpaşa Fen Bilimeri Enstitüsü Bilimsel Araştırma Dergisi 11 (2015) 54-69 .

12. KARAN TÜNAY,TEKIN SABAN, BURSALI AHMET.‘Crimean-Congo Hemorrhagic Fever Virus in Ixodid Ticks in Tokat Province of Turkey. Abstracts / Journal of Biotechnology 161S (2012) 19–48. 

13. Tunay KARAN, Saban Tekin, Adem Keskin, Ahmet Bursalı. Testing The Presence of Tick-Borne Encephalitis Virus in Ixodid Ticks (Acari: Ixodidae) From Tokat and Ordu Vicinity. In vivo International Journal of Experimental and Clinical Pathophysiology and Drug Research. 25:3 467-576 (2011).

14. Tunay KARAN, Omer KAYIR, Zekeriya ALTUNER, Ramazan ERENLER.Growth and norharmane production of Chroococcus minutus under various stress conditions.2018, 1, 10-15.

15.Tunay KARAN.  Metabolic profile and biological activities of Lavandula stoechas L. Cellular and Molecular Biology E-ISSN : 1165-158X / P-ISSN : 0145-5680.

16. Tunay Karan, Ramazan Erenler. Fatty acid constituents and anticancer activity of Cladophora fracta (OF Müller ex Vahl) Kützing. Tropical Journal of Pharmaceutical Research October 2018; 17 (10): 1977-1982.

17. Tunay Karan, Ali Aydin. Anticancer potential and cytotoxic effect of some freshwater cyanobacteria. Tropical Journal of Pharmaceutical Research November 2018; 17 (11): 2183-2188.

18.Evanthia Mantzouki, Tunay KARAN and et. al. Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins. Toxins 2018, 10, 156.

19.Evanthia Mantzouki, Tunay KARAN and et. al. A European Multi Lake Survey dataset of

environmental variables, phytoplankton pigments and cyanotoxins. Scıentıfıc Data 5:180226 DOI: 10.1038/sdata.2018.226.

20. Tunay Karan and Bilge Hilal Cadirci. Evaluatıon of antımıcrobıal and antıoxıdant actıvıty of lepıdıum draba l. World Journal of Pharmaceutical Research, Vol 7, Issue 13, 2018.

Research Interest: Medicinal Chemistry and Drug Design; Organic Synthesis; Bioorganic Chemistry; Biological evaluation of therapeutically-efficient organic compounds, including pharmacodynamics and pharmacokinetics; Molecular modeling and chemoinformatics; Molecular Imaging; Structure elucidation using different spectroscopic techniques (such as MS, IR, 1H NMR, 13C NMR, and 2D NMR such as COSY, HMBC, and HMQC). Purification of products from reaction mixtures both by simple solvent crystallization methods and advanced preparative chromatographic methods.

Hamed received his PhD in mechanical engineering on a collaborative project between the University of Limerick, Imperial College London and Helmholtz-Zentrüm Berlin, titled "Effect of prior deformation on creep behaviour of AISI 316H austenitic stainless steels" funded by Science Foundation Ireland and EDF (formerly British Energy Ltd.).

He worked at the Irish Centre for Composites Research as lecturer in Finite Element Analysis and Aircraft Structures, and as a post-doctoral researcher on three consecutive industrial-oriented projects on composites materials, MAAXIMUS project funded through EU FP7 grant agreement nº213371 led by Airbus (www.maaximus.eu), Design of Optimised Composites for Impact Applications (OPTCOM) project funded by Enterprise Ireland (grant CF/2013/3012B), and the Science Foundation Ireland funded FALCOM project (www.falcom.ie) on a novel adhesively bonded joining technology.

Research Interest: 

•    Airworthiness

•    Composites

•    Computing, Simulation & Modelling

•    Manufacturing of Functional Materials

•    Aerospace Materials

•    Nanomaterials

•    Renewable Energy

•    Smart Materials

•    Structures and Materials

URL: https://www.cranfield.ac.uk/people/dr-hamed-yazdani-nezhad-14085695

List of Publications: 

1.    Deane, S, Avdelidis HP, Ibarra-Castanedo C, Zhang H, Yazdani Nezhad H, Williamson AA, Mackley T, Davis MJ, Maldague X & Tsourdos A (2019) Application of NDT thermographic imaging of aerospace structures, Infrared Physics and Technology, 97 (March) 456-466.
2.    Liu Y, Zhang X, Lemanski S, Yazdani Nezhad H & Ayre D (2019) Experimental and numerical study of process-induced defects and their effect on fatigue debonding in composite joints, International Journal of Fatigue, 125 (August) 47-57.
3.    Sirikham A, Zhao Y, Yazdani Nezhad H, Du W & Roy R (2019) Estimation of damage thickness in fiber-reinforced composites using pulsed thermography, IEEE Transactions on Industrial Informatics, 15 (1) Article No. TII-18-2286 445-453.
4.    Yazdani Nezhad H,Stratakis D, Ayre D, Addepalli S & Zhao Y (2018) Mechanical performance of composite bonded joints in the presence of localised process-induced zero-thickness defects, Procedia Manufacturing, 16 91-98.
5.    Lotfian S, Giraudmaillet C, Yoosefinejad A, Thakur VJ & Yazdani Nezhad H (2018) Electrospun piezoelectric polymer nanofiber layers for enabling in situ measurement in high-performance composite laminates, ACS Omega, 3 (8) 8891-8902.
6.    Mgbemena CO, Li D, Lin MF, Liddel PD, Katnam KB, Kumar VT & Yazdani Nezhad H (2018) Accelerated microwave curing of fibre-reinforced thermoset polymer composites for structural applications: A review of scientific challenges, Composites Part A: Applied Science and Manufacturing, 115 (December) 88-103.
7.    Yazdani Nezhad H & Thakur VJ (2018) Effect of morphological changes due to increasing carbon nanoparticles content on the quasi-static mechanical response of epoxy resin, Polymers, 10 (10) Article No. 1106.
8.    Liu Y, Lemanski S, Zhang X, Ayre D & Yazdani Nezhad H (2018) A finite element study of fatigue crack propagation in single lap bonded joint with process-induced disbond, International Journal of Adhesion and Adhesives, Early online.
9.    Yazdani Nezhad H, Egan B, Merwick F & McCarthy CT (2017) Bearing damage characteristics of fibre-reinforced countersunk composite bolted joints subjected to quasi-static shear loading, Composite Structures, 166 (April) 184-192.
10.    Bhanushali R, Ayre D & Yazdani Nezhad H (2017) Tensile response of adhesively bonded composite-to-composite single-lap joints in the presence of bond deficiency, Procedia CIRP, 59 139-143.
11.    Yazdani Nezhad H, Zhao Y, Liddel PD, Marchante VR & Roy R (2017) A novel process-linked assembly failure model for adhesively bonded composite structures, CIRP Annals - Manufacturing Technology, 66 (1) 29-32. Dataset/s: 10.17862/cranfield.rd.4681009
12.    Yazdani Nezhad H & O'Dowd N (2015) Creep relaxation in the presence of residual stress, Engineering Fracture Mechanics, 138 250-264.
13.    Zhou Y, Yazdani Nezhad H, Hou C, Wan X, McCarthy C & McCarthy M (2015) A three dimensional implicit finite element damage model and its application to single-lap multi-bolt composite joints with variable clearance, Composite Structures, 131 1060-1072.
14.    Yazdani Nezhad H, Merwick F, Frizzell R & McCarthy C (2014) Numerical analysis of low-velocity rigid-body impact response of composite panels, International Journal of Crashworthiness, 20 (1) 27-43.
15.    Zhou Y, Yazdani-Nezhad H, McCarthy M, Wan X & McCarthy C (2014) A study of intra-laminar damage in double-lap, multi-bolt, composite joints with variable clearance using continuum damage mechanics, Composite Structures, 116 441-452.
16.    Yazdani Nezhad H & O'Dowd NP (2012) Study of creep relaxation under combined mechanical and residual stresses, Engineering Fracture Mechanics, 93 132-152.

Research Interest: Antioxidant Activity, Antioxidants, Ethnobotany, Compound Isolation, Bioactivity, Free Radical Scavengers, DPPH, Biotechnology, Essential Oils, Antioxidant Assays, Flavonoids, Phenol, Phytochemicals, Natural Product Chemistry, Chromatography, Natural Product Isolation, Anthocyanins, Extraction, Phytochemical Analysis, Ethnopharmacology, Phytochemical Purification, Herbal Medicine, Biological Activities, Soxhlet Extraction, Natural Product Pharmacology, Antibacterial Activity, Nutraceuticals, Natural Product Drug Discovery, Ethnomedicine, Ethnopharmacy, Chemotaxonomy, Herbal Drug Development, Evaluation of Cytotoxicity, Medicinal and Pharmaceutical Chemistry, Traditional Medicine, Pharmacological Screening, Natural Compound, Fatty acid composition, Fatty acid analysis.Pharmacology, Biochemistry, Natural Products, Chromatography, Asphodeline.

Research Interest: Type III secretion system inhibitors, antitumor agents based on polyol natural products and beta-arrestin agonists.

Research Interest: Nanocosmetics, emulsion investigations, non- invasive bioengineering techniques, polymer formulation, matrix techniques.

Research Interest: Bioactive compounds and Biomaterials.

Research Interest: Using chemical ecology as a tool for the discovery of drugs and eco-friendly agrochemicals, Analytical method development and validation, Biotransformation of naturally occurring bioactive secondary metabolites using Rhizopus spp and Saccharomyces spp and the anti-infective and antioxidant potentials of the derivatives. Evaluation of the nutraceutical potentials of some non-utilised seeds from medicinal plants in Nigeria.

Research Interest:  "Targeted drug delivery; Chemical functionalization of nanoparticles; Chemical composition-biological behavior relationship of nanoparticles; Biomaterials for immunotherapy; Nanomedicine; Pharmaceutical Nanotechnology; Nanovaccines; Immunotoxicity of nanoparticles; Surface biofunctionalization of the nanoparticles with antibodies and peptides; Cell-nanoparticle interactions

"

Research Interest: "Organometallic: Transition Metal-catalyzed Nitrogenation of Hydrocarbons; edicinal Inorganic Chemistry: Ruthenium-based Metallopharmaceuticals; Renewable Biomass Energy: Metal-catalyzed Conversion of Cellulosic Biomass for fuels and value-added chemicals"