Research Interest: Natural Product Chemistry, Medicinal Chemistry, Chemical Biolgoy

Research Interest: Lectin; chitinase; protein; amino acid; nanoparticles; nanomedicine; apoptosis; cell cycle; antibacterial; anticancer; antifungal; gene expression; cell morphology; cytotoxicity; toxicity; antibiofilm; cell culture..

Research Interest: Bioactive compounds and Biomaterials.

Research Interest: Marine natural products (MNPs), in particular the synthesis and structural modification of bioactive MNPs.

Research Interest: Nano chemistry and Nano adsorbent, Composite, hybride material, natural materials, zeolite and clay, Ion exchange, adsorption, chromatography, Analytical chemistry (separation, spectroscopy) Water Treatment 

Research Interest: Design, synthesis, characterization and in vitro and in vivo kinetics of pro-prodrug systems to be used for the delivery for certain drugs that have poor water solubility or/and have low bioavailability using ab initio, DFT, semiempirical, molecular mechanics as well as molecular dynamics and conformational dynamics methods..

Research Interest: Highly efficient chemical synthesis, discovery of new types of drugs and discovery of catalyst and its application. In addition, I interest to synthesis new classes of dendrimer-like polymeric DNA, polymers and its application for chemiluminescence detection of target DNA and delivery of siRNA. I have experience of a wide range of techniques as applied to Medicinal chemistry, including medicinal chemistry, molecular biology, analytical chemistry, spectroscopy, synthetic chemistry and synthetic biology

Research Interest: Food Processing, health food and cosmetics, Research of Chinese herbal medicine research, Agricultural biotechnology, Supercritical fluid, and Mycology

Research Interest: Physical and organic chemistry; Photochemistry; Organic synthesis; Photo-catalysis; Chemo-sensors

Research Interest: Mechanism of action of anticancer platinum/ruthenium drugs in cancer chemotherapy; Targeting BRCA1 DNA repair pathway by platinum/ruthenium drugs in estrogen receptor-positive, estrogen receptor-negative, and BRCA1-associated breast cancers; Mutation screening of breast cancer suppressor gene BRCA1; Functional and structural studies of breast cancer suppressor protein BRCA1; High-throughput genotyping by DHPLC of the dihydropyrimidine dehydrogenase gene

Christoforos G. Kokotos is an Assistant Professor of Organic Chemistry at the Department of Chemistry, National and Kapodistrian University of Athens, Greece, with undergraduate studies at the University of Athens, PhD studies at the University of Bristol, UK (Prof. Varinder Aggarwal) and post-doctoral studies at Princeton University, USA (Prof. David W. C. MacMillan). His research interests focus on the development of novel asymmetric organocatalytic methodologies, green and sustainable organocatalytic oxidations, Photocatalysis, their application in the synthesis of pharmaceuticals, compounds of biological importance and natural products and the study of the mechanisms of organic transformations employing modern techniques, like HRMS. He is co-author of 71 peer-reviewed papers, 4 book chapters, 2 patents, >40 presentations in conferences. He is the recipient of prestigious awards, like the Hildergard-Zervas Award, Academy of Athens (2016 and 2018), JSP fellowship for the Burgenstock Conference (2016), Young Investigators Workshop (3 times representing Greece, 2014, 2017 and 2018) and ACS Young Academic Investigators Award (2014, representing Europe).

Research Interest: Organic Chemistry, Food Chemistry, Green Chemistry

Grants: (1) Research Funding Scheme Post-doc, “PEPCAT-Novel Organocatalysts Based on Peptides and Amino Acids and their Application in Asymmetric Organic Transformations”, General Secretariat for Research and Development (2012-2015, 150.000 €).

(2) Organocatalysis – ORCA, Cost Action CM0905 funded by the intergovernmental framework for European Cooperation in Science and technology (2011-2014), Management Committee Substitute and co-Organizer of the third ORCA meeting in Athens, 2012. Action Chair: Prof. P. Pihko, University of Jyvskyl, Finland.

(3) Research Proposal Funding Scheme, John Latsis Foundation “PhotoOrganocatalysis: Development of new environmentally-friendly methods for the synthesis of compounds for the pharmaceutical and chemical industry” (2015, 12.000€).

(4) C-H Activation in Organic Synthesis – CHAOS, Cost Action CM15106 funded by the intergovernmental framework for European Cooperation in Science and technology (2016-2020), Management Committee Substitute. Action Chair: Prof. M. Schnurch, Technical University of Vienna, Austria.

(5) Fellowship for PhD programme, Ms Errika Voutyritsa, State Scholarships Foundation (IKY), 2016.

(6) Fellowship for PhD programme, Ms Ierasia Triandafillidi, Hellenic Foundation for Research and Innovation (ELIDEK), 2017.

(7) Fellowship for PhD programme, Mr Nikolaos Nikitas, State Scholarships Foundation, 2018.

(8) European Network on Pseudomyxoma Peritonei – PMP, Cost Action CA17101 funded by the intergovernmental framework for European Cooperation in Science and technology (2019-2023), Management Committee Member. Action Chair: Prof. Kjersti Flatmark, Oslo University Hospital, Norway.

(9) Chemobrionics, Cost Action CA17120 funded by the intergovernmental framework for European Cooperation in Science and technology (2019-2023), Management Committee Member. Action Chair: Prof. Julyan Cartwright, CSIC Granada, Spain.

(10) Fellowship for PhD programme, Ms Nikoleta Spiliopoulou, Hellenic Foundation for Research and Innovation (ELIDEK), 2019.

(11) Research Funding Scheme Teams of Young Investigators, “Green and Sustainable Organocatalysis: Novel Epoxidation reactions and their application in Chemical Industry”, General Secretariat for Research and Development (2019-2021, 50.000 €).

List of Publications:1.    “Photoorganocatalytic Synthesis of Acetals from Aldehydes” N. F. Nikitas, I. Triandafillidi and C. G. Kokotos*, Green Chem., 2019, 21, 669-674. (citations: 0) (Impact factor: 8.59)

2.    “Enantioselective Organocatalytic Enamine C-H Oxidation/Diels-Alder Reaction” Z. Dzambaski, D.-I. Tzaras, S. Lee, C. G. Kokotos and B. P. Bondzic*, Adv. Synth. Catal., 2019, 361, 1792-1797. (citations: 0) (Impact factor: 5.12)

3.    “Photocatalytic Atom Transfer Radical Addition to Olefins utilizing Novel Photocatalysts” E. Voutyritsa, I. Triandafillidi, N. V. Tzouras, N. F. Nikitas, E. K. Pefkianakis, G. C. Vougioukalakis and C. G. Kokotos*, Molecules, 2019, 24, 1644-1653. (citations: 0) (Impact factor: 3.09)

4.    “Photocatalytic Synthesis of γ-Lactones from Alkenes: High-Resolution Mass Spectrometry as a Tool to Study Photoredox Reactions” I. Triandafillidi, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2018, 20, 36-39. (citations: 8) (Impact factor: 6.49)

5.    “Organocatalytic Synthesis of Oxazolines and Dihydrooxazines from Allyl-Amides: Bypassing the Inherent Regioselectivity of the Cyclization” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Adv. Synth. Catal., 2018, 360, 951-957. (citations: 0) (Impact factor: 5.12)

6.    “Green Photo-Organocatalytic C−H Activation of Aldehydes: Selective Hydroacylation of Electron-Deficient Alkenes” G. N. Papadopoulos, E. Voutyritsa, N. Kaplaneris and C. G. Kokotos*, Chem. Eur. J., 2018, 24, 1726-1731. (citations: 2) (Impact factor: 5.16)

7.    “Expanding the Scope of Photocatalysis: Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, ChemCatChem, 2018, 10, 2466-2470. (citations: 1) (Impact factor: 4.67)

8.    “Photoorganocatalysis, Small Organic Molecules and Light in the Service of Organic Synthesis: the Awakening of a Sleeping Giant” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Org. Biomol. Chem., 2018, 16, 4596-4614. Invited Review. (citations: 7) (Impact factor: 3.56)

9.    “Combining Οrganocatalysis with Photoorganocatalysis: Photocatalytic Hydroacylation of Asymmetric Organocatalytic Michael Addition Products” A. Schiza, N. Spiliopoulou,  A. Shahu and C. G. Kokotos*, New J. Chem., 2018, 42, 18844-18849. (citations: 7) (Impact factor: 3.28)

10.    “Proline Dipeptides Containing Fluorine Moieties as Organocatalysts for the Asymmetric Aldol Reaction” A. Ahmetlli, N. Spiliopoulou, A. Magi-Oikonomopoulou, D.-T. Gerokonstantis, P. Moutevelis-Minakakis* and C. G. Kokotos*, Tetrahedron, 2018, 74, 5987-5995. (citations: 0) (Impact factor: 2.65)

11.    “Green Organocatalytic Oxidative Methods using Activated Ketones” I. Triandafillidi, D. I. Tzaras, and C. G. Kokotos*, ChemCatChem, 2018, 10, 2521-2535. (citations: 1) (Impact factor: 4.67)

12.    “Combining Prolinamides with 2-Pyrrolidinone: Novel Organocatalysts for the Asymmetric Aldol Reaction” I. Vlasserou, M. Sfetsa, D. T. Gerokonstantis, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2018, 74, 2338-2349. (citations: 3) (Impact factor: 2.65)

13.    “Photoorganocatalytic Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, N. F. Nikitas, M. K. Apostolopoulou, A. D. D. Gerogiannopoulou and C. G. Kokotos*, Synthesis, 2018, 50, 3395-3401. Invited Contribution for Special Issue: Photoredox Methods and their Strategic Applications in Synthesis (citations: 0) (Impact factor: 2.72).

14.    “Green Photoorganocatalytic Synthesis of Phenols from Arylboronic Acids” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Synlett, 2018, 29, 1324-1328. Invited Contribution for Special Issue: 9th EuCheMS Organic Division Young Investigator Workshop (citations: 3) (Impact factor: 2.37)

15.    “Organocatalytic Synthesis of Lactones by the Oxidation of Alkenoic Acids” I. Triandafillidi, M. Raftopoulou, A. Savvidou, and C. G. Kokotos*, ChemCatChem, 2017, 9, 4120-4124. (citations: 3) (Impact factor: 4.67)

16.    “Photoorganocatalytic Synthesis of Lactones via a Selective C–H Activation–alkylation of Alcohols” N. Kaplaneris, A. Bisticha, G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Green Chem., 2017, 19, 4451-4456. (citations: 11) (Impact factor: 8.59)

17.    “Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes” G. S. Koutoulogenis, M. G. Kokotou, E. Voutyritsa, D. Limnios, C. G. Kokotos*, Org Lett., 2017, 19, 1760-1763. (citations: 11) (Impact factor: 6.49)

18.    “Organocatalytic Oxidation of Substituted Anilines to Azoxybenzenes and Nitro Compounds: Mechanistic Studies Excluding the Involvement of a Dioxirane Intermediate” E. Voutyritsa, A. Theodorou, M. G. Kokotou and C. G. Kokotos*, Green Chem., 2017, 1291-1298. (citations: 14) (Impact factor: 8.59) 2017 Green Chemistry Hot

19.    “Green Organocatalytic Synthesis of Indolines and Pyrrolidines from Alkenes” A. Theodorou and C. G. Kokotos*, Adv. Synth. Catal., 2017, 359, 1577-1581. (citations: 9) (Impact factor: 5.12)

20.    “Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes” I. Triandafillidi and C. G. Kokotos*, Org. Lett., 2017, 19, 106-109. (citations: 17) (Impact factor: 6.49)

21.    “Photoinitiated Thiol-Ene “Click” Reaction: An Organocatalytic Alternative” D. Limnios and C. G. Kokotos*, Adv. Synth. Catal., 2017, 19, 1291-1298. (citations: 20) (Impact factor: 5.12)

22.    “Organocatalytic Synthesis of Polysubstituted Tetrahydrofurans from Alkenes” A. Theodorou and C. G. Kokotos*, Green Chem., 2017, 19, 670-674. (citations: 11) (Impact factor: 8.59)

23.    “Green Organocatalytic Dihydroxylation of Alkenes” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Eur. J. Org. Chem., 2017, 11, 1502-1509. (citations: 5) (Impact factor: 2.88)

24.    “Green Organocatalytic Synthesis of Dihydrobenzofurans by Oxidation-Cyclization of Allylphenols” I. Triandafillidi, I. K. Sideri, D. I. Tzaras, N. Spiliopoulou and C. G. Kokotos*, Synthesis, 2017, 49, 4254-4260. Invited Contribution for Special Issue: Modern Strategies in Cyclization Reactions (citations: 2) (Impact factor: 2.77).

25.    “Green Organocatalytic Oxidation of Sulfides to Sulfoxides and Sulfones” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, Synthesis, 2017, 49, 917-924. Invited Contribution for Burgenstock Conference (citations: 13) (Impact factor: 2.77).

26.    “Enantioselective Organocatalytic Synthesis of 2-Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate” N. Kaplaneris, C. Spyropoulos, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2016, 18, 5800-5803. (citations: 5) (Impact factor: 6.49)

27.    “One-pot Amide Bond Formation from Aldehydes and Amines via a Photoorganocatalytic Activation of Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, J. Org. Chem., 2016, 81, 7023-7028. (citations: 17) (Impact factor: 4.81)

28.    “Photoorganocatalytic One-pot Synthesis of Hydroxamic Acids from Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, Chem. Eur. J., 2016, 22, 6964-6967. (citations: 27) (Impact factor: 5.12)

29.    “Green Organocatalytic α-Hydroxylation of Ketones” E. Voutyritsa, A. Theodorou and C. G. Kokotos*, Org. Biomol. Chem., 2016, 14, 5708-5713. Invited Article for the Special Thematic issue “New Talent in Organic and Medicinal Chemistry”. (citations: 10) (Impact factor: 3.56)

30.    “(Thio)urea-mediated Synthesis of Functionalized Six-membered Rings with Multiple Chiral Centers” G. Koutoulogenis, N. Kaplaneris and C. G. Kokotos*, Beilstein J. Org. Chem., 2016, 12, 462-495. Invited Article for the Special issue “Multifunctional Organocatalysis”. (citations: 19) (Impact factor: 2.76)

31.    “4-Fluoro and 4-Hydroxy Pyrrolidine-thioxotetrahydropyrimidinones: Organocatalysts for Green Asymmetric Transformations in Brine” N. Kaplaneris, G. Koutoulogenis, M. Raftopoulou and C. G. Kokotos*, J. Org. Chem., 2015, 80, 5464-6473. (citations: 21) (Impact factor: 4.81)

32.    “tert-Butyl Esters of Peptides as Organocatalysts for the Asymmetric Aldol Reaction” A. Bisticha, I. Triandafillidi and C. G. Kokotos*, Tetrahedron: Asymmetry, 2015, 26, 102-108. (citations: 15) (Impact factor: 2.13)

33.    “One-pot Synthesis of O-Allylhydroxylamines through the Organocatalytic Oxidation of Tertiary Allylic Amines followed by a [2,3]-Meisenheimer Rearrangement” A. Theodorou, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2015, 21, 5238-5241. (citations: 20) (Impact factor: 5.12)

34.    “tert-Butyl Ester or Benzylamide of the Dipeptide Pro-Gly as Organocatalysts for the Asymmetric Aldol Reaction” I. Triandafillidi, A. Bisticha, E. Voutyritsa, G. Galiatsatou and C. G. Kokotos*, Tetrahedron, 2015, 71, 932-940. (citations: 20) (Impact factor: 2.65)

35.    “Conjugating Proline Derivatives onto Multi-walled Carbon Nanotubes: Preparation, Characterization and Catalytic Activity in Water” D. D. Chronopoulos, C. G. Kokotos, M. Tsakos, N. Karousis, G. Kokotos and N. Tagmatarchis, Mat. Lett., 2015, 157, 212-214. (citations: 5) (Impact factor: 2.69)

36.    “Functionalized Multi-walled Carbon Nanotubes in an Aldol Reactions” D. D. Chronopoulos, C. G. Kokotos, N. Karousis, G. Kokotos* and N. Tagmatarchis*, Nanoscale, 2015, 7, 2750-2757. (citations: 8) (Impact factor: 7.23)

37.    “Organocatalytic Oxidation Reactions” D. Limnios and C. G. Kokotos*, Current Organocatalysis, 2015, 2, 171-190. (citations: 3) (Impact factor: -)

38.    “Fullerene-proline Hybrids: Synthesis, Characterization and Organocatalytic Properties in Aldol Reactions” D. D. Chronopoulos, M. Tsakos, N. Karousis, C. G. Kokotos* and N. Tagmatarchis*, Mat. Lett., 2014, 137, 343-346. (citations: 11) (Impact factor: 2.69)

39.    “Photoorganocatalytic Hydroacylation of Dialkyl Azodicarboxylates by utilizing Activated Ketones as Photocatalysts” G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 13811-13814. (citations: 24) (Impact factor: 5.12)

40.    “2,2,2-Trifluoroacetophenone: An Organocatalyst for an Environmentally Friendly Epoxidation of Alkenes” D. Limnios and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4270-4276. (citations: 37). Feature Article, ACS Editors Choice Article, Top Read Article for the last 12 months, Highlighted at TCI catalogue for 2,2,2-trifluoroacetophenone. (Impact factor: 4.81)

41.    “One-pot Synthesis of Ureas from Boc-Protected Amines” C. Spyropoulos and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4477-4483. (citations: 30) (Impact factor: 4.81)

42.    “2,2,2-Trifluoroacetophenone as an Organocatalyst for the Oxidation of Tertiary Amines and Azines to N-Oxides” D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 559-563. (citations: 34) (Impact factor: 5.12)

43.    “tert-Butyl Esters of Tripeptides based on Pro-Phe as Organocatalysts for the Asymmetric Aldol Reaction in Aqueous or Organic Medium” A. Psarra, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2014, 70, 608-615. (citations: 29) (Impact factor: 2.65)

44.    “Primary and Secondary Amine-(thio)ureas and Squaramides and their Applications in Asymmetric Organocatalysis” M. Tsakos and C. G. Kokotos*, Tetrahedron, 2013, 69, 10199-10222. (citations: 91) (Impact factor: 2.65)

45.    “Organocatalytic Oxidation of Organosilanes to Silanols” D. Limnios and C. G. Kokotos*, ACS Catalysis, 2013, 3, 2239-2243. (citations: 33) (Impact factor: 11.38)

46.    “β-tert-Butyl Aspartate as an Organocatalyst for the Asymmetric α-Amination of α,α-Disubstituted Aldehydes” A. Theodorou, G. N. Papadopoulos and C. G. Kokotos*, Tetrahedron, 2013, 69, 5438-5443. (citations: 23) (Impact factor: 2.65)

47.    “An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides leading to a One-pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids” C. G. Kokotos*, Org. Lett., 2013, 15, 2406-2409. (citations: 49) (Impact factor: 6.49)

48.    “Microwave-Assisted Organocatalytic Cross-Aldol Condensation of Aldehydes” D. Limnios and C. G. Kokotos*, RSC Adv., 2013, 3, 4496-4499. (citations: 16) (Impact factor: 2.94)

49.    “Organocatalytic Asymmetric Domino Michael-Henry Reaction for the Synthesis of Substituted Bicyclo[3.2.1]octan-2-ones” M. Tsakos, M. R. J. Elsegood and C. G. Kokotos*, Chem. Commun., 2013, 49, 2219-2221. (citations: 45) (Impact factor: 6.29)

50.    “Novel Prolinamide-Ureas as Organocatalysts for the Asymmetric Aldol Reaction” P. Revelou, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2012, 68, 8732-8738. (citations: 28) (Impact factor: 2.65)

51.    “Pyrrolidine-thioxotetrahydropyrimidinone as an Efficient Organocatalyst for the Enantioselective Michael Addition of Cyclic Ketones to Nitrodienes” M. Tsakos. M. Trifonidou and C. G. Kokotos*, Tetrahedron, 2012, 68, 8630-8635. (citations: 13) (Impact factor: 2.65)

52.    “A Tripeptide-like Prolinamide-Thiourea as an Aldol Reaction Catalyst” S. Fotaras, C. G. Kokotos and G. Kokotos, Org. Biomol. Chem., 2012, 10, 5613-5619. (citations: 35) (Impact factor: 3.56) 

53.    “Primary Amine-Thioureas with Improved Catalytic Properties for “Difficult” Michael Reactions. Efficient Organocatalytic Syntheses of (S)-, (R)-Baclofen and (S)-Phenibut” M. Tsakos, C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2012, 354, 740-746. (citations: 47) (Impact factor: 5.12)

54.    “Enantioselective Organocatalytic α-Alkylation of Ketones Utilising SN-1 Type Reaction of Alcohols” M. Trifonidou and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 1563-1568. (citations: 33) (Impact factor: 2.88)

55.    “Construction of Tertiary Alcohols Bearing Perfluoroalkyl Chains Catalyzed by Prolinamide-Thioureas” C. G. Kokotos*, J. Org. Chem., 2012, 77, 1131-1135. (citations: 46) (Impact factor: 4.81)

56.    “Organocatalytic “Difficult” Michael Reaction of Ketones with Nitrodienes Utilising Primary Amine-Thioureas Based on di-tert-Butyl Esters of Aspartic Acid” M. Tsakos and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 576-580. (citations: 24) (Impact factor: 2.88)

57.    “Novel Pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as Highly Effective Catalysts for the Asymmetric Michael Addition” C. G. Kokotos, D. Limnios, D. Triggidou, M. Trifonidou and G. Kokotos, Org. Biom. Chem., 2011, 9, 3386-3395. (citations: 37) (Impact factor: 3.56) 

58.    “Prolinamides bearing Thiourea Groups as Catalysts for Asymmetric Aldol Reactions” S. Fotaras, C. G. Kokotos, E. Tsandi and G. Kokotos, Eur. J. Org. Chem., 2011, 1310-1317. (citations: 50) (Impact factor: 2.88)

59.    “Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-independent Phospholipase A2” G. Kokotos, Y.-H. Hsu, J. Burke, C. Baskakis, C. G. Kokotos, V. Magrioti and E. A. Dennis, J. Med. Chem., 2010, 53, 3602-3610. (citations: 53) (Impact factor: 6.26)

60.    “Interactions at the Bilayer Interface and Receptor Site Induced by the Novel Synthetic Pyrrolidinone Analog MMK3” C. Fotakis, S. Gega, E. Siapi, C. Potamitis, K. Viras, P. Moutevelis-Minakakis, C. G. Kokotos, S. Durdagi, S. Golic Grdadolnik, B. Sartori, M. Rappolt and T. Mavromoustakos, Biochim. Biophys. Acta Biomembranes, 2010, 1798, 422-432. (citations: 23) (Impact factor: 3.44) 

61.    “Bacillus subtilis Esterase (BS2) and its Double Mutant have Different Selectivity in the Removal of Carboxyl Protecting Groups” E. Barbayianni, C. G. Kokotos, S. Bartsch, C. Drakou, U. Bornscheuer and G. Kokotos, Adv. Synth. Catal., 2009, 351, 2325-2332. (citations: 10) (Impact factor: 5.12) 

62.    “Primary Amine-thioureas based on tert-Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction” C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2009, 351, 1355-1362. (citations: 71) (Impact factor: 5.12) 

63.    “Sulfonamides of Homoproline and Dipeptides as Organocatalysts for Michael and Aldol Reactions” E. Tsandi, C. G. Kokotos, S. Kousidou, V. Ragoussis and G. Kokotos, Tetrahedron, 2009, 65, 1444-1449. (citations: 50) (Impact factor: 2.65) 

64.    “Synthesis of Medicinally Interesting Polyfluoro Ketones via Perfluoroalkyl Lithium Reagents” C. G. Kokotos, C. Baskakis and G. Kokotos, J. Org. Chem., 2008, 73, 8623-8626. (citations: 24) (Impact factor: 4.81)

65.    “Sulfur Ylide Mediated Three-component Aziridination and Epoxidation Reactions using Vinyl Sulfonium Salts” C. G. Kokotos, E. M. McGarrigle and V. K. Aggarwal, Synlett, 2008, 2191-2195, highlighted in Synfacts, 2008, 11, 1142. (citations: 24) (Impact factor: 2.37)

66.    “Aminals as Substrates for Sulfur Ylides: A Synthesis of Functionalised Aziridines and N-Heterocycles” C. G. Kokotos and V. K. Aggarwal, Org. Lett., 2007, 9, 2099-2102. (citations: 39) (Impact factor: 6.49)

67.    “A Practical Synthesis of a [2.2.1] Bicyclic Chiral Sulfide for Asymmetric Transformations” V. K. Aggarwal, G. Fang, C. G. Kokotos, J. Richardson and M. G. Unthank, Tetrahedron, 2006, 62, 11297-11303. (citations: 26) (Impact factor: 2.65)  

68.    “Hemi-aminals as Substrates for Sulfur Ylides: Direct Asymmetric Syntheses of Functionalised Pyrrolidines and Piperidines” C. G. Kokotos and V. K. Aggarwal, Chem. Commun., 2006, 2156-2158. (citations: 42) (Impact factor: 6.29)   

69.    “Synthesis, Binding Studies, and in vivo Biological Evaluation of Novel non-Peptide Antihypertensive Analogues” T. Mavromoustakos, P. Moutevelis-Minakakis, C. G. Kokotos, P. Kontogianni, A. Politi, P. Zoumpoulakis, J. Findlay, A. Cox, A. Balmforth, A. Zoga and E. Iliodromitis, Bioorg. Med. Chem., 2006, 14, 4353-4360. (citations: 21) (Impact factor: 2.79)

70.    “Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal PGE2 Release” T. L. Yaksh, G. Kokotos, C. I. Svensson, D. Stephens, C. G. Kokotos, B. Fitzsimmons, D. Hadjipavlou-Litina, X. Y. Hua and E. A. Dennis, J. Pharmacol. Exp. Ther., 2006, 316, 466-475. (citations: 56) (Impact factor: 3.87)

71.    “Synthesis and Activity of 2-Oxoamides containing Long Chain β-Amino Acids” V. Constantinou-Kokotou, A. Peristeraki, C. G. Kokotos, D. A. Six and E. A. Dennis, J. Peptide Sci., 2005, 11, 431-435. (citations: 18) (Impact factor: 1.55)

Research Interest: Pharmaceutical organic chemistry and Pharmaceutical analytical chemistry; Development of chromatographic and immunoassay methods for analyzing different pharmaceutical compounds in biological fluids which could be used in bio-studies.  drug-drug interactions and drug-juice interaction and on the synthesis of some Barbituric acid and Imidazole derivatives and their application in pharmaceutical products. NMR, X-ray, LC/MS, HPLC and ELISA.

Research Interest: Photocatalysis, colloid and interfacial phenomenon, CO2 capture and storage, multiphase flow in porous materials,

Grants:
 i) 5.2018-5.2020, UGC-UKIERI, £50000, Novel EOR technique for the depleted oil reservoirs of Upper Assam Basin with simultaneous CO2 Capture and Sequestration. (PI)
(ii) 10.2017-9.2018, EPSRC, £10000, EPSRC Formulations for collaboration with the University of Nottingham
(iii) 8.2016 - 7.2019, EPSRC, EP/N024672/1, £1,226,534, A compact CO2 capture process to combat industrial emissions.
(iv) 2013 - 9. 2015 Royal Society of Edinburgh, Removal of SOx and NOx from fossil fuel combustion, £11,600.
(v) 1.2013 - 4.2016, EPSRC, EP/J019720/1, £832,807, Feasibility of a wetting layer absorption carbon capture process based on chemical solvents. For this project, I supervised a research associate working on microwave swing adsorption for CO2 capture.
(vi) 2012-2013, Royal Academy of Engineering, Study on phosphorylated hollow silica / polysulfone hybrid membrane for the treatment of wastewater containing oil, £24000.
(vii) 2011-2014, EPSRC, EP/I010939/1, £664,440, FOCUS – Fundamentals of Optimised Capture Using Solids: circulating fluidised bed CO2 capture processes for coal-fired power plants based on amine-functionalised adsorbents.
(viii) 10/2011 - 9/2014, PhD studentship, Carnegie Trust for the Universities of Scotland, Transport of three phase flow in porous media for CO2 storage and enhanced oil recovery, £60,000.
(ix) 2010-2011 Research Grant from the Royal Society, £17,745,

URL: https://www.eng.ed.ac.uk/about/people/dr-xianfeng-fan

List of Publications

1.    C. Chao, X. Jin, L. Teng, A.A. Stokes, X. Fan, Bubble Dislodgment in a Capillary Network with Microscopic Multichannels and Multibifurcation Features, Langmuir, 2019, DOI: 10.1021/acs.langmuir.8b03323

2.    E Al-Zaidi, X Fan*, Liquid CO2 behaviour during water displacement in a sandstone core sample, Journal of Natural Gas Science and Engineering 62, 259-274, 2019

3.    C Chao, G Xu, X Fan*, Effect of surface tension, viscosity, pore geometry and pore contact angle on effective pore throat, Chemical Engineering Science, 197, 269-279, 2019

4.    E Al-Zaidi, K Edlmann, X Fan*, Gaseous CO2 behaviour during water displacement in a sandstone core sample, International Journal of Greenhouse Gas Control 80, 32-42, 2019

5.    C Chao, X Xu, SO Kwelle, X Fan*, Significance of gas-liquid interfaces for two-phase flows in micro-channels, Chemical Engineering Science 192, 114-125, 2018

6.    E Al-Zaidi, X Fan*, K Edlmann, Supercritical CO2 behaviour during water displacement in a sandstone core sample, International Journal of Greenhouse Gas Control 79, 200-211, 2018

7.    F Bougie, X Fan*, Microwave regeneration of monoethanolamine aqueous solutions used for CO2 capture, International Journal of Greenhouse Gas Control 79, 165-172, 2018

8.    L Liu, H Chen, E Shiko, X Fan, Y Zhou, G Zhang, X Luo, XE Hu, Low-cost DETA impregnation of acid-activated sepiolite for CO2 capture, Chemical Engineering Journal 353, 940-948, 2018

9.    E Al-Zaidi, J Nash, X Fan*, Effect of CO2 phase on its water displacements in a sandstone core sample, International Journal of Greenhouse Gas Control 71, 227-238, 2018

10.    E Al-Zaidi, X Fan*, Effect of aqueous electrolyte concentration and valency on contact angle on flat glass surfaces and inside capillary glass tubes, Colloids and Surfaces A: Physicochemical and Engineering Aspects 543, 1-8, 2018

11.    E Al-Zaidi, X Fan*, K Edlmann, The Effect of CO2 Phase on Oil Displacement in a Sandstone Core Sample, Fluids 3 (1), 23-, 2018

12.    Y. Guo*, H. Wu, X. Fan*, L. Zhoua, Q. Chen, Palladium composite membrane fabricated on rough porous alumina tube without intermediate layer for hydrogen separation, International Journal of Hydrogen Energy, 42, 9958–9965, 2017.

13.    Y. Guo, Y. Jin, H Wu, D. Li, X. Fan, Direct synthesis of propylene oxide using hydrogen peroxide in a membrane reactor, Chemical Papers, 71, 49-57, 2017

14.    S.J. McGurk, C.F. Martín, S. Brandani, M.B. Sweatman, X. Fan*, Microwave Swing Regeneration of Aqueous Monoethanolamine for Post-Combustion CO2 Capture, Applied Energy, 192, 126–133, 2017

15.    S. Farrukh, X. Fan, A. Hussain, A comparative CO2 adsorption analysis in pure and amine modified composite membranes. Polymer-Plastics Technology and Engineering, 56, 1158–1166, 2017

16.    C.F. Martín, M.B. Sweatman, S. Brandani, X. Fan*, Wet impregnation of a commercial low cost silica using DETA for a fast post-combustion CO2 capture process, Applied Energy, 183, 1705–1721, 2016.

17.    Dne. Nagy, D. Nagy, I.M Szilagyicd, X. Fan*, Effect of the morphology and phases of WO3 nanocrystals on their photocatalytic efficiency, RSC Adv. 6, 33743, 2016. 1 citation.

18.    D Nagy, T Firkala, X Fan†, I.M. Szilágyi, A study of the effect of the morphology on the photocatalytic activity of WO3,  Eur. Chem. Bull., 5, 40-42, 2016

19.    S. Hafeez, X. Fan†, A. Hussain, C.F. Martín, CO2 adsorption using TiO2 composite polymeric membranes: A kinetic study, Journal of Environmental Sciences, 35, 163-171, 2015. 2 citations.

20.    X. Li, X. Fan*, Effect of CO2 phase on contact angle in oil-wet and water-wet pores, International Journal of Greenhouse Gas Control, 36, 106-113, 2015. 8 citations.

21.    X. Li, H. Fan, X. Fan*, Effect of chemical structure of organics on pore wetting, Chemical Engineering Science, 137, 458-465, 2015. 1 citation

22.    S. Hafeez, X. Fan†, A. Hussain, A Kinetic Study of CO2 Adsorption in Cellulose Acetate Membranes, International Journal of Environmental Science and Development, 6, 755-759, 2015.