Research Interest: Medicinal chemistry,Histology and Embryology.

Christoforos G. Kokotos is an Assistant Professor of Organic Chemistry at the Department of Chemistry, National and Kapodistrian University of Athens, Greece, with undergraduate studies at the University of Athens, PhD studies at the University of Bristol, UK (Prof. Varinder Aggarwal) and post-doctoral studies at Princeton University, USA (Prof. David W. C. MacMillan). His research interests focus on the development of novel asymmetric organocatalytic methodologies, green and sustainable organocatalytic oxidations, Photocatalysis, their application in the synthesis of pharmaceuticals, compounds of biological importance and natural products and the study of the mechanisms of organic transformations employing modern techniques, like HRMS. He is co-author of 71 peer-reviewed papers, 4 book chapters, 2 patents, >40 presentations in conferences. He is the recipient of prestigious awards, like the Hildergard-Zervas Award, Academy of Athens (2016 and 2018), JSP fellowship for the Burgenstock Conference (2016), Young Investigators Workshop (3 times representing Greece, 2014, 2017 and 2018) and ACS Young Academic Investigators Award (2014, representing Europe).

Research Interest: Organic Chemistry, Food Chemistry, Green Chemistry

Grants: (1) Research Funding Scheme Post-doc, “PEPCAT-Novel Organocatalysts Based on Peptides and Amino Acids and their Application in Asymmetric Organic Transformations”, General Secretariat for Research and Development (2012-2015, 150.000 €).

(2) Organocatalysis – ORCA, Cost Action CM0905 funded by the intergovernmental framework for European Cooperation in Science and technology (2011-2014), Management Committee Substitute and co-Organizer of the third ORCA meeting in Athens, 2012. Action Chair: Prof. P. Pihko, University of Jyvskyl, Finland.

(3) Research Proposal Funding Scheme, John Latsis Foundation “PhotoOrganocatalysis: Development of new environmentally-friendly methods for the synthesis of compounds for the pharmaceutical and chemical industry” (2015, 12.000€).

(4) C-H Activation in Organic Synthesis – CHAOS, Cost Action CM15106 funded by the intergovernmental framework for European Cooperation in Science and technology (2016-2020), Management Committee Substitute. Action Chair: Prof. M. Schnurch, Technical University of Vienna, Austria.

(5) Fellowship for PhD programme, Ms Errika Voutyritsa, State Scholarships Foundation (IKY), 2016.

(6) Fellowship for PhD programme, Ms Ierasia Triandafillidi, Hellenic Foundation for Research and Innovation (ELIDEK), 2017.

(7) Fellowship for PhD programme, Mr Nikolaos Nikitas, State Scholarships Foundation, 2018.

(8) European Network on Pseudomyxoma Peritonei – PMP, Cost Action CA17101 funded by the intergovernmental framework for European Cooperation in Science and technology (2019-2023), Management Committee Member. Action Chair: Prof. Kjersti Flatmark, Oslo University Hospital, Norway.

(9) Chemobrionics, Cost Action CA17120 funded by the intergovernmental framework for European Cooperation in Science and technology (2019-2023), Management Committee Member. Action Chair: Prof. Julyan Cartwright, CSIC Granada, Spain.

(10) Fellowship for PhD programme, Ms Nikoleta Spiliopoulou, Hellenic Foundation for Research and Innovation (ELIDEK), 2019.

(11) Research Funding Scheme Teams of Young Investigators, “Green and Sustainable Organocatalysis: Novel Epoxidation reactions and their application in Chemical Industry”, General Secretariat for Research and Development (2019-2021, 50.000 €).

List of Publications:1.    “Photoorganocatalytic Synthesis of Acetals from Aldehydes” N. F. Nikitas, I. Triandafillidi and C. G. Kokotos*, Green Chem., 2019, 21, 669-674. (citations: 0) (Impact factor: 8.59)

2.    “Enantioselective Organocatalytic Enamine C-H Oxidation/Diels-Alder Reaction” Z. Dzambaski, D.-I. Tzaras, S. Lee, C. G. Kokotos and B. P. Bondzic*, Adv. Synth. Catal., 2019, 361, 1792-1797. (citations: 0) (Impact factor: 5.12)

3.    “Photocatalytic Atom Transfer Radical Addition to Olefins utilizing Novel Photocatalysts” E. Voutyritsa, I. Triandafillidi, N. V. Tzouras, N. F. Nikitas, E. K. Pefkianakis, G. C. Vougioukalakis and C. G. Kokotos*, Molecules, 2019, 24, 1644-1653. (citations: 0) (Impact factor: 3.09)

4.    “Photocatalytic Synthesis of γ-Lactones from Alkenes: High-Resolution Mass Spectrometry as a Tool to Study Photoredox Reactions” I. Triandafillidi, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2018, 20, 36-39. (citations: 8) (Impact factor: 6.49)

5.    “Organocatalytic Synthesis of Oxazolines and Dihydrooxazines from Allyl-Amides: Bypassing the Inherent Regioselectivity of the Cyclization” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Adv. Synth. Catal., 2018, 360, 951-957. (citations: 0) (Impact factor: 5.12)

6.    “Green Photo-Organocatalytic C−H Activation of Aldehydes: Selective Hydroacylation of Electron-Deficient Alkenes” G. N. Papadopoulos, E. Voutyritsa, N. Kaplaneris and C. G. Kokotos*, Chem. Eur. J., 2018, 24, 1726-1731. (citations: 2) (Impact factor: 5.16)

7.    “Expanding the Scope of Photocatalysis: Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, ChemCatChem, 2018, 10, 2466-2470. (citations: 1) (Impact factor: 4.67)

8.    “Photoorganocatalysis, Small Organic Molecules and Light in the Service of Organic Synthesis: the Awakening of a Sleeping Giant” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Org. Biomol. Chem., 2018, 16, 4596-4614. Invited Review. (citations: 7) (Impact factor: 3.56)

9.    “Combining Οrganocatalysis with Photoorganocatalysis: Photocatalytic Hydroacylation of Asymmetric Organocatalytic Michael Addition Products” A. Schiza, N. Spiliopoulou,  A. Shahu and C. G. Kokotos*, New J. Chem., 2018, 42, 18844-18849. (citations: 7) (Impact factor: 3.28)

10.    “Proline Dipeptides Containing Fluorine Moieties as Organocatalysts for the Asymmetric Aldol Reaction” A. Ahmetlli, N. Spiliopoulou, A. Magi-Oikonomopoulou, D.-T. Gerokonstantis, P. Moutevelis-Minakakis* and C. G. Kokotos*, Tetrahedron, 2018, 74, 5987-5995. (citations: 0) (Impact factor: 2.65)

11.    “Green Organocatalytic Oxidative Methods using Activated Ketones” I. Triandafillidi, D. I. Tzaras, and C. G. Kokotos*, ChemCatChem, 2018, 10, 2521-2535. (citations: 1) (Impact factor: 4.67)

12.    “Combining Prolinamides with 2-Pyrrolidinone: Novel Organocatalysts for the Asymmetric Aldol Reaction” I. Vlasserou, M. Sfetsa, D. T. Gerokonstantis, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2018, 74, 2338-2349. (citations: 3) (Impact factor: 2.65)

13.    “Photoorganocatalytic Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins” E. Voutyritsa, N. F. Nikitas, M. K. Apostolopoulou, A. D. D. Gerogiannopoulou and C. G. Kokotos*, Synthesis, 2018, 50, 3395-3401. Invited Contribution for Special Issue: Photoredox Methods and their Strategic Applications in Synthesis (citations: 0) (Impact factor: 2.72).

14.    “Green Photoorganocatalytic Synthesis of Phenols from Arylboronic Acids” I. K. Sideri, E. Voutyritsa and C. G. Kokotos*, Synlett, 2018, 29, 1324-1328. Invited Contribution for Special Issue: 9th EuCheMS Organic Division Young Investigator Workshop (citations: 3) (Impact factor: 2.37)

15.    “Organocatalytic Synthesis of Lactones by the Oxidation of Alkenoic Acids” I. Triandafillidi, M. Raftopoulou, A. Savvidou, and C. G. Kokotos*, ChemCatChem, 2017, 9, 4120-4124. (citations: 3) (Impact factor: 4.67)

16.    “Photoorganocatalytic Synthesis of Lactones via a Selective C–H Activation–alkylation of Alcohols” N. Kaplaneris, A. Bisticha, G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Green Chem., 2017, 19, 4451-4456. (citations: 11) (Impact factor: 8.59)

17.    “Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes” G. S. Koutoulogenis, M. G. Kokotou, E. Voutyritsa, D. Limnios, C. G. Kokotos*, Org Lett., 2017, 19, 1760-1763. (citations: 11) (Impact factor: 6.49)

18.    “Organocatalytic Oxidation of Substituted Anilines to Azoxybenzenes and Nitro Compounds: Mechanistic Studies Excluding the Involvement of a Dioxirane Intermediate” E. Voutyritsa, A. Theodorou, M. G. Kokotou and C. G. Kokotos*, Green Chem., 2017, 1291-1298. (citations: 14) (Impact factor: 8.59) 2017 Green Chemistry Hot

19.    “Green Organocatalytic Synthesis of Indolines and Pyrrolidines from Alkenes” A. Theodorou and C. G. Kokotos*, Adv. Synth. Catal., 2017, 359, 1577-1581. (citations: 9) (Impact factor: 5.12)

20.    “Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes” I. Triandafillidi and C. G. Kokotos*, Org. Lett., 2017, 19, 106-109. (citations: 17) (Impact factor: 6.49)

21.    “Photoinitiated Thiol-Ene “Click” Reaction: An Organocatalytic Alternative” D. Limnios and C. G. Kokotos*, Adv. Synth. Catal., 2017, 19, 1291-1298. (citations: 20) (Impact factor: 5.12)

22.    “Organocatalytic Synthesis of Polysubstituted Tetrahydrofurans from Alkenes” A. Theodorou and C. G. Kokotos*, Green Chem., 2017, 19, 670-674. (citations: 11) (Impact factor: 8.59)

23.    “Green Organocatalytic Dihydroxylation of Alkenes” A. Theodorou, I. Triandafillidi and C. G. Kokotos*, Eur. J. Org. Chem., 2017, 11, 1502-1509. (citations: 5) (Impact factor: 2.88)

24.    “Green Organocatalytic Synthesis of Dihydrobenzofurans by Oxidation-Cyclization of Allylphenols” I. Triandafillidi, I. K. Sideri, D. I. Tzaras, N. Spiliopoulou and C. G. Kokotos*, Synthesis, 2017, 49, 4254-4260. Invited Contribution for Special Issue: Modern Strategies in Cyclization Reactions (citations: 2) (Impact factor: 2.77).

25.    “Green Organocatalytic Oxidation of Sulfides to Sulfoxides and Sulfones” E. Voutyritsa, I. Triandafillidi and C. G. Kokotos*, Synthesis, 2017, 49, 917-924. Invited Contribution for Burgenstock Conference (citations: 13) (Impact factor: 2.77).

26.    “Enantioselective Organocatalytic Synthesis of 2-Oxopiperazines from Aldehydes: Identification of the Elusive Epoxy Lactone Intermediate” N. Kaplaneris, C. Spyropoulos, M. G. Kokotou and C. G. Kokotos*, Org. Lett., 2016, 18, 5800-5803. (citations: 5) (Impact factor: 6.49)

27.    “One-pot Amide Bond Formation from Aldehydes and Amines via a Photoorganocatalytic Activation of Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, J. Org. Chem., 2016, 81, 7023-7028. (citations: 17) (Impact factor: 4.81)

28.    “Photoorganocatalytic One-pot Synthesis of Hydroxamic Acids from Aldehydes” G. N. Papadopoulos and C. G. Kokotos*, Chem. Eur. J., 2016, 22, 6964-6967. (citations: 27) (Impact factor: 5.12)

29.    “Green Organocatalytic α-Hydroxylation of Ketones” E. Voutyritsa, A. Theodorou and C. G. Kokotos*, Org. Biomol. Chem., 2016, 14, 5708-5713. Invited Article for the Special Thematic issue “New Talent in Organic and Medicinal Chemistry”. (citations: 10) (Impact factor: 3.56)

30.    “(Thio)urea-mediated Synthesis of Functionalized Six-membered Rings with Multiple Chiral Centers” G. Koutoulogenis, N. Kaplaneris and C. G. Kokotos*, Beilstein J. Org. Chem., 2016, 12, 462-495. Invited Article for the Special issue “Multifunctional Organocatalysis”. (citations: 19) (Impact factor: 2.76)

31.    “4-Fluoro and 4-Hydroxy Pyrrolidine-thioxotetrahydropyrimidinones: Organocatalysts for Green Asymmetric Transformations in Brine” N. Kaplaneris, G. Koutoulogenis, M. Raftopoulou and C. G. Kokotos*, J. Org. Chem., 2015, 80, 5464-6473. (citations: 21) (Impact factor: 4.81)

32.    “tert-Butyl Esters of Peptides as Organocatalysts for the Asymmetric Aldol Reaction” A. Bisticha, I. Triandafillidi and C. G. Kokotos*, Tetrahedron: Asymmetry, 2015, 26, 102-108. (citations: 15) (Impact factor: 2.13)

33.    “One-pot Synthesis of O-Allylhydroxylamines through the Organocatalytic Oxidation of Tertiary Allylic Amines followed by a [2,3]-Meisenheimer Rearrangement” A. Theodorou, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2015, 21, 5238-5241. (citations: 20) (Impact factor: 5.12)

34.    “tert-Butyl Ester or Benzylamide of the Dipeptide Pro-Gly as Organocatalysts for the Asymmetric Aldol Reaction” I. Triandafillidi, A. Bisticha, E. Voutyritsa, G. Galiatsatou and C. G. Kokotos*, Tetrahedron, 2015, 71, 932-940. (citations: 20) (Impact factor: 2.65)

35.    “Conjugating Proline Derivatives onto Multi-walled Carbon Nanotubes: Preparation, Characterization and Catalytic Activity in Water” D. D. Chronopoulos, C. G. Kokotos, M. Tsakos, N. Karousis, G. Kokotos and N. Tagmatarchis, Mat. Lett., 2015, 157, 212-214. (citations: 5) (Impact factor: 2.69)

36.    “Functionalized Multi-walled Carbon Nanotubes in an Aldol Reactions” D. D. Chronopoulos, C. G. Kokotos, N. Karousis, G. Kokotos* and N. Tagmatarchis*, Nanoscale, 2015, 7, 2750-2757. (citations: 8) (Impact factor: 7.23)

37.    “Organocatalytic Oxidation Reactions” D. Limnios and C. G. Kokotos*, Current Organocatalysis, 2015, 2, 171-190. (citations: 3) (Impact factor: -)

38.    “Fullerene-proline Hybrids: Synthesis, Characterization and Organocatalytic Properties in Aldol Reactions” D. D. Chronopoulos, M. Tsakos, N. Karousis, C. G. Kokotos* and N. Tagmatarchis*, Mat. Lett., 2014, 137, 343-346. (citations: 11) (Impact factor: 2.69)

39.    “Photoorganocatalytic Hydroacylation of Dialkyl Azodicarboxylates by utilizing Activated Ketones as Photocatalysts” G. N. Papadopoulos, D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 13811-13814. (citations: 24) (Impact factor: 5.12)

40.    “2,2,2-Trifluoroacetophenone: An Organocatalyst for an Environmentally Friendly Epoxidation of Alkenes” D. Limnios and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4270-4276. (citations: 37). Feature Article, ACS Editors Choice Article, Top Read Article for the last 12 months, Highlighted at TCI catalogue for 2,2,2-trifluoroacetophenone. (Impact factor: 4.81)

41.    “One-pot Synthesis of Ureas from Boc-Protected Amines” C. Spyropoulos and C. G. Kokotos*, J. Org. Chem., 2014, 79, 4477-4483. (citations: 30) (Impact factor: 4.81)

42.    “2,2,2-Trifluoroacetophenone as an Organocatalyst for the Oxidation of Tertiary Amines and Azines to N-Oxides” D. Limnios and C. G. Kokotos*, Chem. Eur. J., 2014, 20, 559-563. (citations: 34) (Impact factor: 5.12)

43.    “tert-Butyl Esters of Tripeptides based on Pro-Phe as Organocatalysts for the Asymmetric Aldol Reaction in Aqueous or Organic Medium” A. Psarra, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2014, 70, 608-615. (citations: 29) (Impact factor: 2.65)

44.    “Primary and Secondary Amine-(thio)ureas and Squaramides and their Applications in Asymmetric Organocatalysis” M. Tsakos and C. G. Kokotos*, Tetrahedron, 2013, 69, 10199-10222. (citations: 91) (Impact factor: 2.65)

45.    “Organocatalytic Oxidation of Organosilanes to Silanols” D. Limnios and C. G. Kokotos*, ACS Catalysis, 2013, 3, 2239-2243. (citations: 33) (Impact factor: 11.38)

46.    “β-tert-Butyl Aspartate as an Organocatalyst for the Asymmetric α-Amination of α,α-Disubstituted Aldehydes” A. Theodorou, G. N. Papadopoulos and C. G. Kokotos*, Tetrahedron, 2013, 69, 5438-5443. (citations: 23) (Impact factor: 2.65)

47.    “An Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides leading to a One-pot Enantioselective Synthesis of Lactones Catalyzed by Amino Acids” C. G. Kokotos*, Org. Lett., 2013, 15, 2406-2409. (citations: 49) (Impact factor: 6.49)

48.    “Microwave-Assisted Organocatalytic Cross-Aldol Condensation of Aldehydes” D. Limnios and C. G. Kokotos*, RSC Adv., 2013, 3, 4496-4499. (citations: 16) (Impact factor: 2.94)

49.    “Organocatalytic Asymmetric Domino Michael-Henry Reaction for the Synthesis of Substituted Bicyclo[3.2.1]octan-2-ones” M. Tsakos, M. R. J. Elsegood and C. G. Kokotos*, Chem. Commun., 2013, 49, 2219-2221. (citations: 45) (Impact factor: 6.29)

50.    “Novel Prolinamide-Ureas as Organocatalysts for the Asymmetric Aldol Reaction” P. Revelou, C. G. Kokotos* and P. Moutevelis-Minakakis*, Tetrahedron, 2012, 68, 8732-8738. (citations: 28) (Impact factor: 2.65)

51.    “Pyrrolidine-thioxotetrahydropyrimidinone as an Efficient Organocatalyst for the Enantioselective Michael Addition of Cyclic Ketones to Nitrodienes” M. Tsakos. M. Trifonidou and C. G. Kokotos*, Tetrahedron, 2012, 68, 8630-8635. (citations: 13) (Impact factor: 2.65)

52.    “A Tripeptide-like Prolinamide-Thiourea as an Aldol Reaction Catalyst” S. Fotaras, C. G. Kokotos and G. Kokotos, Org. Biomol. Chem., 2012, 10, 5613-5619. (citations: 35) (Impact factor: 3.56) 

53.    “Primary Amine-Thioureas with Improved Catalytic Properties for “Difficult” Michael Reactions. Efficient Organocatalytic Syntheses of (S)-, (R)-Baclofen and (S)-Phenibut” M. Tsakos, C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2012, 354, 740-746. (citations: 47) (Impact factor: 5.12)

54.    “Enantioselective Organocatalytic α-Alkylation of Ketones Utilising SN-1 Type Reaction of Alcohols” M. Trifonidou and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 1563-1568. (citations: 33) (Impact factor: 2.88)

55.    “Construction of Tertiary Alcohols Bearing Perfluoroalkyl Chains Catalyzed by Prolinamide-Thioureas” C. G. Kokotos*, J. Org. Chem., 2012, 77, 1131-1135. (citations: 46) (Impact factor: 4.81)

56.    “Organocatalytic “Difficult” Michael Reaction of Ketones with Nitrodienes Utilising Primary Amine-Thioureas Based on di-tert-Butyl Esters of Aspartic Acid” M. Tsakos and C. G. Kokotos*, Eur. J. Org. Chem., 2012, 576-580. (citations: 24) (Impact factor: 2.88)

57.    “Novel Pyrrolidine-thiohydantoins/thioxotetrahydropyrimidinones as Highly Effective Catalysts for the Asymmetric Michael Addition” C. G. Kokotos, D. Limnios, D. Triggidou, M. Trifonidou and G. Kokotos, Org. Biom. Chem., 2011, 9, 3386-3395. (citations: 37) (Impact factor: 3.56) 

58.    “Prolinamides bearing Thiourea Groups as Catalysts for Asymmetric Aldol Reactions” S. Fotaras, C. G. Kokotos, E. Tsandi and G. Kokotos, Eur. J. Org. Chem., 2011, 1310-1317. (citations: 50) (Impact factor: 2.88)

59.    “Potent and Selective Fluoroketone Inhibitors of Group VIA Calcium-independent Phospholipase A2” G. Kokotos, Y.-H. Hsu, J. Burke, C. Baskakis, C. G. Kokotos, V. Magrioti and E. A. Dennis, J. Med. Chem., 2010, 53, 3602-3610. (citations: 53) (Impact factor: 6.26)

60.    “Interactions at the Bilayer Interface and Receptor Site Induced by the Novel Synthetic Pyrrolidinone Analog MMK3” C. Fotakis, S. Gega, E. Siapi, C. Potamitis, K. Viras, P. Moutevelis-Minakakis, C. G. Kokotos, S. Durdagi, S. Golic Grdadolnik, B. Sartori, M. Rappolt and T. Mavromoustakos, Biochim. Biophys. Acta Biomembranes, 2010, 1798, 422-432. (citations: 23) (Impact factor: 3.44) 

61.    “Bacillus subtilis Esterase (BS2) and its Double Mutant have Different Selectivity in the Removal of Carboxyl Protecting Groups” E. Barbayianni, C. G. Kokotos, S. Bartsch, C. Drakou, U. Bornscheuer and G. Kokotos, Adv. Synth. Catal., 2009, 351, 2325-2332. (citations: 10) (Impact factor: 5.12) 

62.    “Primary Amine-thioureas based on tert-Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction” C. G. Kokotos and G. Kokotos, Adv. Synth. Catal., 2009, 351, 1355-1362. (citations: 71) (Impact factor: 5.12) 

63.    “Sulfonamides of Homoproline and Dipeptides as Organocatalysts for Michael and Aldol Reactions” E. Tsandi, C. G. Kokotos, S. Kousidou, V. Ragoussis and G. Kokotos, Tetrahedron, 2009, 65, 1444-1449. (citations: 50) (Impact factor: 2.65) 

64.    “Synthesis of Medicinally Interesting Polyfluoro Ketones via Perfluoroalkyl Lithium Reagents” C. G. Kokotos, C. Baskakis and G. Kokotos, J. Org. Chem., 2008, 73, 8623-8626. (citations: 24) (Impact factor: 4.81)

65.    “Sulfur Ylide Mediated Three-component Aziridination and Epoxidation Reactions using Vinyl Sulfonium Salts” C. G. Kokotos, E. M. McGarrigle and V. K. Aggarwal, Synlett, 2008, 2191-2195, highlighted in Synfacts, 2008, 11, 1142. (citations: 24) (Impact factor: 2.37)

66.    “Aminals as Substrates for Sulfur Ylides: A Synthesis of Functionalised Aziridines and N-Heterocycles” C. G. Kokotos and V. K. Aggarwal, Org. Lett., 2007, 9, 2099-2102. (citations: 39) (Impact factor: 6.49)

67.    “A Practical Synthesis of a [2.2.1] Bicyclic Chiral Sulfide for Asymmetric Transformations” V. K. Aggarwal, G. Fang, C. G. Kokotos, J. Richardson and M. G. Unthank, Tetrahedron, 2006, 62, 11297-11303. (citations: 26) (Impact factor: 2.65)  

68.    “Hemi-aminals as Substrates for Sulfur Ylides: Direct Asymmetric Syntheses of Functionalised Pyrrolidines and Piperidines” C. G. Kokotos and V. K. Aggarwal, Chem. Commun., 2006, 2156-2158. (citations: 42) (Impact factor: 6.29)   

69.    “Synthesis, Binding Studies, and in vivo Biological Evaluation of Novel non-Peptide Antihypertensive Analogues” T. Mavromoustakos, P. Moutevelis-Minakakis, C. G. Kokotos, P. Kontogianni, A. Politi, P. Zoumpoulakis, J. Findlay, A. Cox, A. Balmforth, A. Zoga and E. Iliodromitis, Bioorg. Med. Chem., 2006, 14, 4353-4360. (citations: 21) (Impact factor: 2.79)

70.    “Systemic and Intrathecal Effects of a Novel Series of Phospholipase A2 Inhibitors on Hyperalgesia and Spinal PGE2 Release” T. L. Yaksh, G. Kokotos, C. I. Svensson, D. Stephens, C. G. Kokotos, B. Fitzsimmons, D. Hadjipavlou-Litina, X. Y. Hua and E. A. Dennis, J. Pharmacol. Exp. Ther., 2006, 316, 466-475. (citations: 56) (Impact factor: 3.87)

71.    “Synthesis and Activity of 2-Oxoamides containing Long Chain β-Amino Acids” V. Constantinou-Kokotou, A. Peristeraki, C. G. Kokotos, D. A. Six and E. A. Dennis, J. Peptide Sci., 2005, 11, 431-435. (citations: 18) (Impact factor: 1.55)

Research Interest: QSAR, DFT, Transition State Theory, Ab initio Methods, electronic structure, reactivity indices

Ramazan Erenler is a full Professor in the Department of Chemistry, Faculty of Arts and Sciences Tokat Gaziosmanpasa University, Turkey, head of the Synthetic Organic Chemistry Laboratory and Plant Research Laboratory. He has completed his PhD in the field of Organic Chemistry from Tokat Gaziosmanpasa Universiyt, Turkey and postdoctoral studies from Academia Sinica, Taiwan, and Kansas State University, USA in synthetic Organic Chemistry. Dr. Erenler visited some European universities for seminars and research. He has published seventy eight (78) scientific articles in peer reviewed journals. He joined the many international congresses and publised 110 conference proceedings. Dr. Erenler’s research focuses on the area of Plant Chemistry, isolation and identification of secondary metabolites from plants and investigation of their antioxidant and anticancer activities.

Research Interest: Natural Product Chemistry, Organic Chemistry, Synthesis, Isolation and identification of active compounds from plants, Spectroscopy, Chromatography, Biological activity, Antioxidant activity, Anticancer activity

List of Publications: 

Papers (SCI)

1. Topçu, G.; Erenler, R.; Çakmak, O.; Johansson, C. B.; Çelik, C; Chai, H.-B. Pezzuto, J, M. Diterpenes from the berries of juniperus excelsa. Phytochemistry,  50, 1195-1199 (1999).

2. Demirtas, İ; Erenler, R.; ve  Çakmak, O. Synthetic route to 1,3-disubstituted naphthalene derivatives, Journal of Chemical Research (S), 524-526. (2002).

3. Çelik, İ; Demirtaş, İ; Akkurt, M.; Erenler, R.; Güven, K.; Çakmak, O. Crystal  Structure of  cis,cis,cis-1,2-epoxy-3,5-dibromo-4-hydroxy tetralin, Crystal Research and Technology, 38, 2,193-196. (2003).

4. Elmastaş, M.; Öztürk, L.; Gökçe, İ.; Erenler, R.; Aboul-Enein, H. Y.,  Determination of antioxidant activity of marshmallow flowers (Althea officinalis L.). Analitical Letters, 37, 9, 1859-1861 (2004).

5. Çelik, İ.; Akkurt M.; Demirtas, İ.; Erenler, R. ve Güven, K., The Crystal structure of -phenil-N-thioacetylmorpholine. Analytical Science, 20, x89-x90 (2004).

6. Öztürk, S.; Büyükkıdan, B.; Erenler, R.; Akkkurt, M.; Çakmak, O. ve Fun, H-K. Crystal Structure of 1,4-dihydroxy-3,4-dibromo-1,2,3,4-tetrahydro-napthalene. Cryst. Res. Technol. 39, 9, 815-820. (2004).

7. Akkurt, M.; Çelik, İ.; Erenler, R.; Çakmak, O.; Ersanli, C. C.; Büyükgüngör, O., Trans,trans,trans-2,3,5,8-tetrabro-1,4-dihydroxy- 1,2,3,4-tetrahydro-naphthalene. Acta Crystallograpica Section E, E60, 2096-2098, (2004).

8. Erenler, R. ve Çakmak, O., Synthesis of hexabromo, hydroxy, epoxy, methoxy, and nitroxy derivatives of tetralins and naphthalenes. J. Chem. Res., 8, 566-569, (2004).

9. Erenler, R. and Biellmann, J-F. Facile conversion of pyridine propargylic alcohols to enones: stereochemistry of protonation of allenol. Tet. lett., 46, 34, 5683-5685. (2005).

10. Çakmak, O.; Erenler, R.; Tutar, A.; Celik, N. Synthesis of New Anthrecene Derivatives. J. Org. Chem. 71, 5, 1795-1801, (2006).

11. Çelik, İ.; Akkurt, M.; Erenler, R.; Cakmak O. and Ersanlı, C. C., trans, trans, trans-1,4-Dimethoxy-2,3,5,8-tetrabromotetralin. Acta Crystallograpica Section E, E62, 4609-4610, (2006).

12. Erenler, R.; Synthesizing of 1-phenyl-3-(pyridine-4-yl)prop-2-ynyl acetate. Asian Journal Of Chemistry, 19, 3, 2207-2210 (2007).

13. Erenler, R.; Demirtas, İ; Büyükkıdan, B.; ve Çakmak, O., Synthesis of hydroxy, epoxy, nitroxy and methoxy derivatives of tetralins and naphthalenes. J. Chem. Reseach., 753-757, (2006).

14. Erenler, R. and Biellmann,J. F. ; Synthesis of pentafluorophenyl- and pyridinyl-3 allenes. J. Chem. Soc. China, 54(1),103-108, (2007).

15. Erenler,  R. Synthesıs of allenic naphthalene derivatives. Bull. Chem. Soc. Ethiop. 2007, 21(2), 241-247.

16. İ. Çelik, R. Erenler, M. Akkurt, C. Sancak Ünlü, A. Tutar ve S. Garcia-Granda. Crystal structure of 1,2,3-tribromobenz[f]indane. Analytıcal Scıences 2007, Vol. 23, X229.

17. Erenler, R., Uno M, Goud TV, Biellmann JF. Preparation of some heterocyclic enones and ynones by isomerisation of the propargylic alcohols. J.Chem.Res.7, 459-464, 2009.

18. Ramazan Erenler, Synthesis and Characterization of Pyridyl Propargyloximes. Asian Journal of Chemistry, 23, 8, 3546-3548, 2011.

19. Ramazan Erenler, Facile and Efficient Synthesis of Ethyl 3-oxo-3-(pyridin-4-yl)-2-((pyridin-4-yl)methylene)propanoate, Asian Journal of Chemistry, 23, 8, 3763-3764, 2011.

20. Unsalan, O., Tutar, A., Unlu, C.S., Erenler, R. FTIR spectroscopic and quantum-chemical studies on some tribromoindenes and their isomers, OPTICS AND SPECTROSCOPY, 111, 6, 894-903, 2011

21. İsmail Çelik, Mehmet Akkurt, Ahmet Tutar, Ramazan Erenler and Santiago Garcia-Granda. 2,3-Dihydro-1H-cyclopenta[b]naphthalen-1-ol. Acta Cryst. (2012). E68, o687.

22. İsmail Celik, Mehmet Akkurt, Makbule Yılmaz, Ahmet Tutar, Ramazan Erenler and Santiago Garcia-Granda, 5-Amino-4-bromo-2,3-dihydro-1Hinden-1-one, Acta Crystallographica Section E, 68, 0833. 2012

23. Ismail Celik, Mehmet Akkurt, Makbule Yılmaz, Ahmet Turar, Ramazan Erenler, Canan Kazak. 2,4-Dibromo-2,3-dihydro-1H-inden-1-yl-acetate. Acta Crystallographica Section E, 68, 01884. 2012

24. Cihansel Sancak Unlu, Ahmet Tutar, Ramazan Erenler. Facile and Efficient Bromination of Benz[F]Indan-1-One. J.Chem.Soc.Pak., Vol. 34, No. 3, 705-708, 2012,

25. Ramazan Erenler and Jean-François Biellmann, 1-Methyl-4-ethynylpridinum triflate: Reaction with thiophenol giving rise to chromophoric (E)-1-methyl-4-[2-(phenylsulfanyl)-1-ethenyl]pyridinium triflate. An example of nucleophilic reaction on triple bond, . J.Chem.Soc.Pak., Vol. 34, No.5, 1224-1228, 2012

26. Ahmet Tutar, Ramazan Erenler. Bromination of Benz[f]indene: Synthesis of New Benz[f]indane Derivatives, J.Chem.Soc.Pak. Vol:34, No:6, 1526-1530, (2012).

27. Ismail Celik, Mehmet Akkurt, Makbule Yilmaz, Ahmet Tutar, Ramazan Erenler and Santiago Garcia-Granda. 2,5-Dibromoindan-1-ol. Acta Cryst. (2012). E68, o2795–o2796

28. Ibrahim Demirtas, Ramazan Erenler, Mahfuz Elmastas, Ahmet Goktasoglu. Studies on the antioxidant potential of water-soluble fraction and isolated flavones of Allium vineale. Food Chemistry, 136, (2013) 34-40.

29. Ayse Sahin Yaglıoglu, Bayram Akdulum, Ramazan Erenler, Ibrahim demirtas, Isa Telci, Saban Tekin. Antiproliferative activity of pentadeca-(9e, 13zdien-11-yn-2-one 1 and (e)-1,8-pentadecadiene 2 from Echinacea pallida (nutt.) nutt. Roots. Medicinal Chemistry Research. (2013), 22:2946-2953, DOI: 10.1007/s000-012-0297-2.

30. Makbule Yılmaz, Ahmet Tutar, Ramazan Erenler. Synthesis of Bromoaminoindane and Bromoaminoindanone Derivatives. J. Chem. Res. 4, 232-235 (2013).

31. Salih Ökten, Osman Çakmak, Ramazan Erenler, Önem Yüce, Şaban Tekin. A simple and convenient preparation of novel 6,8-disubstituted quinoline derivatives and their promising anticancer activities. Turk J Chem. (2013) 37: 896-908.

32. Ahmet Tutar, Ramazan Erenler, Jean-François Biellmann. Synthesis of 8-substituted 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene dyes (BODIPY). J. Chem. Soc. Pak., 35, No.4, 1197-1201 (2013).

33. K. Geetha, M. Umadevi, G.V. Sathe, R. Erenler. Spectroscopic investigations on the orientation of1,4-dibromonaphthalene on silver nanoparticles.  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 116 (2013) 236–241.

34. Ramazan Erenler, Sakine Yilmaz, Huseyin Aksit, Ozkan Sen, Nusret Genc, Mahfuz Elmastas and Ibrahim Demirtas. Antioxidant Activities of Chemical Constituents Isolated from Echinops orientalis Trauv. Record of Natural Product, 8:1 (2014)32-36.

35. Hüseyin Akşit, Süleyman M. Çelik, Özkan Şen, Ramazan Erenler, İbrahim Demirtaş, İsa Telci, Mahfuz Elmastaş. Complete Isolation and characterisation of Polar Portion of Mentha dumetorum water extract. Record of Natural Product. 8:3, 277-280, 2014.

36. Jianyu Lu, Izumi Maezawa, Sahani Weerasekara, Ramazan Erenler, Tuyen D. T. Nguyen, James Nguyen, Luxi Z. Swisher, Jun Li, Lee-Way Jin, Alok Ranjan, Sanjay K. Srivastava, Duy H. Hua. Syntheses, neural protective activities, and inhibition of glycogen synthase kinase-3b of substituted quinolines. Bioorganic & Medicinal Chemistry Letters. 24, 3392–3397 (2014).

37. Salih ÖKTEN, Ramazan ERENLER, Tuğba KUL KÖPRÜLÜ, Şaban TEKİN. In vitro antiproliferative / cytotoxic activity of 2,3'-biindole against various cancer cell lines. Turkish Journal of Biology. (2015) 39: 15-22.

38. Ramazan Erenler, Isa Telci, Musa Ulutas, Ibrahim Demirtas, Fatih Gul, Mahfuz Elmastas and Omer Kayir. Chemical Constituents, Quantitative Analysis and Antioxidant Activities of Echinacea purpurea (L.) Moench and Echinacea pallida (Nutt.) Nutt. Journal of Food Biochemistry. (2015).  39 (2015) 622–630.

DOI:10.1111/jfbc.12168

39. Mahfuz Elmastaş, İsa Telci, Hüseyin Akşit, Ramazan Erenler. Comparison of total phenolic contents and antioxidant capacities in mint genotypes used as spices. Turkish Journal of Biochemistry – Türk Biyokimya Dergisi 2015; 40(6): 456–462. DOI: 10.1515/tjb-2015-0034.

40. Mahfuz Elmastas, Ramazan Erenler, Besir Isnac, Huseyin Aksit, Ozkan Sen, Nusret Genc & Ibrahim Demirtas. Isolation and identification of a new neo-clerodane diterpenoid from Teucrium chamaedrys L. Natural Product Research, Vol. 30, No. 3, 299–304, 2016. http://dx.doi.org/10.1080/14786419.2015.1057583.

41. Ramazan Erenler, Ozkan Sen, Ayse Sahin Yaglioglu ve Ibrahim Demirtas. Bioactivity-guided Isolation of Antiproliferative Sesquiterpene Lactones from Centaurea solstitialis L. ssp. Solstitialis. Combinatorial Chemistry & High Throughput Screening, 2016, 19, 66-72.

42. Ramazan Erenler, Ozkan Sen, Huseyin Aksit, Ibrahim Demirtas, Mahfuz Elmastas, İsa Telci. Isolation and identification of chemical constituents from Origanum majorana and investigation of antioxidant activities. Journal of the Science of Food and Agriculture. (2016), 96: 822–836. Doi: 10.1002/jsfa.7155.

43. Ramazan Erenler, Ozkan Sen, Ilyas Yildiz and Ali Aydın. Antiproliferative Activities of Chemical Constituents Isolated from Thymus praecox subsp. grossheimii (Ronniger) Jalas. Rec. Nat. Prod. 10:6 (2016) 766-770.

44. Ramazan Erenler, Koksal Pabuccu, Ayse Sahin Yaglioglu, Ibrahim Demirtas and Fatih Gul. Chemical constituents and antiproliferative effects of cultured Mougeotia nummuloides and Spirulina major against cancerous cell lines. Z. Naturforsch. 2016; 71(3-4)c: 87–92.

45. İsmail Celik, Cem Cuneyt Ersanlı, Rahmi Koseoglu, Huseyin Aksit, Ramazan Erenler, Ibrahim Demirtas¸ and Mehmet Akkurt. Crystal structure of 3,4a,7,7,10a-pentamethyl-3- vinyldodecahydro-1H-benzo[f]chromen-9-ol isolated from Sideritis perfoliata. Acta Cryst. (2016). E72, 1380–1382.

46. Ahmet Tutar, Ramazan Erenler. Bromination of 4-Bromoindanone and 5-Bromoindanone, Facile Synthetic Access to 3,5,10-tribromo-7H-benzo[c]fluoren-7-one. J.Chem.Soc.Pak., Vol. 38, No. 03, 2016. 546-552.

47. Ilyas Yildiz, Ozkan Sen, Ramazan Erenler, Ibrahim Demirtas & Lutfi Behcet. Bioactivity–guided isolation of flavonoids from Cynanchum acutum L. subsp. sibiricum (willd.) Rech. f. and investigation of their antiproliferative activity. Natural Product Research. 2017.  http://dx.doi.org/10.1080/14786419.2017.1289201.

48. Abdussamat Guzel, Huseyin Aksit, Mahfuz Elmastas, Ramazan Erenler. Bioassay-guided isolation and identification of antioxidant flavonoids from Cyclotrichium origanifolium (Labill.) Manden and Scheng. 2017. Pharmacognosy Magazine 2017;13:316-20.

49. Ramazan Erenler, Bilal Meral, Ozkan Sen, Mahfuz Elmastas, Ali Aydin, Ozgur Eminagaoglu & Gulacti Topcu. Bioassay-guided isolation, identification of compounds from Origanum rotundifolium and investigation of their antiproliferative and antioxidant activities. PHARMACEUTICAL BIOLOGY, 2017 VOL. 55, NO. 1, 1646–1653.

50. Tunay Karan, Ramazan Erenler. Screening of Norharmane from Seven Cyanobacteria by High‑performance Liquid Chromatography. Pharmacognosy Magazine. Volume 13 | Issue 51 | July-September 2017 (Supplement 3).

51.Tunay Karan, Ilyas Yildiz, Ali Aydin and Ramazan Erenler. Inhibition of Various Cancer Cells Proliferation of Bornyl Acetate and Essential Oil from Inula graveolens (Linnaeus) Desf. Rec. Nat. Prod. (2018) 12:3 273-283.

52. Tunay Karan, Ramazan Erenler. Fatty acid constituents and anticancer activity of

Cladophora fracta (OF Müller ex Vahl) Kützing. Tropical Journal of Pharmaceutical Research 2018; 17 (10): 1977-1982.

53. Perihan Koysu, Nusret Genc, Mahfuz Elmastas, Huseyin Aksit, Ramazan Erenler Isolation, identification of secondary metabolites from Salvia absconditiflora and evaluation of their antioxidative properties. Natural product research. https://doi.org/10.1080/14786419.2018.1488700.

54. Ramazan ERENLER, İsa TELCİ, Mahfuz ELMASTAŞ, Hüseyin AKSİT, Fatih GÜL, Ali Rıza TÜFEKÇİ, İbrahim DEMİRTAŞ, Ömer KAYIR. Quantification of flavonoids isolated from Mentha spicata in selected clones of Turkish mint landraces. Turk J Chem (2018) 42: 1695 – 1705.

55. F Gokalp, R Erenler. Theoretical Study of Synthesis of 1, 3-dibromonaphthanlene. JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN 40 (6), 1089-1092

56. M Elmastas, SM Celik, N Genc, H Aksit, R Erenler, İ Gulcin. Antioxidant activity of an anatolian herbal tea—Origanum minutiflorum: isolation and characterization of its secondary metabolites. International Journal of Food Properties 21 (1), 374-384

Other Publication:

1. Abser, M. N.; Karim, M. M.; Kausar, A.; Matin, M. A.; Molla, M. E.; Yeasmin, Z. and    Erenler, R. Synthesis and Liquid Crystalıne Behavior of bis[N-(3-Hydrazinato]Nikel (II) Complexes. Jahangirnagar University Journal of Science, 28, 7-21, (2005).

2. M. N. Abser, M. M. Alam, M. R. Alam, M. Hossain, M. M. Karim, M. A. Matin, M. E. Molla and R. Erenler. Synthesis and Characterisation of Some Chlorobenzylidene Derivatives of Aroylhydrazinatonicel (II) Complexes. Jahangirnagar University Journal of Science, Vol:29, 1-8, 2006.

3. D. Çelik, A. Tutar, R. Erenler. Short and Selective Synthesis of 3,5-dibromoinden-1-one, Journal of New Results in Science, 1, 1-4, 2012.

4. İbrahim DEMİRTAŞ, Nuri Kaan İNAH, Serkan KOLDAŞ, Ömer Cem KARAKOÇ, Ali Rıza TÜFEKÇ, Fatih GÜL, İsa TELCİ, Ramazan ERENLER, Muhammed ALTUN. Değerlendiremediğimiz Tarım Ürünleri Potansiyelimiz. Tarım Bilimleri Araştırma Dergisi 6 (1): 168-173, 2013 ISSN: 1308-3945, E-ISSN: 1308-027X, www.nobel.gen.tr

5. Necla Türkmen, Ayşenur Öz, Aslı Sönmez, Tuğçe Erola, Deniz Gülümser, Burcu Yurdakul, Ömer Kayır, Mahfuz Elmastas, Ramazan Erenler. Chemical Composition of Essential Oil from Rosmarinus Officinalis L. Leaves. Journal of New Results in Science 6 (2014) 27-31.

6. Burcu Bayir, Hatice Gündüz,  Tuba Usta, Esma Şahin, Zeynep Özdemir, Ömer Kayıra, Özkan Şen, Hüseyin Akşit, Mahfuz Elmastaş, Ramazan Erenler. Chemical Composition of Essential Oil from Marrubium Vulgare L. Leaves. Journal of New Results in Science 6 (2014) 44-50.

7. Gamze Kaya, Rukiye Karakaya, Esma Tilgel, Merve Sandikçı, Esra Yücel, Gayya Çicek, Ömer Kayır, Hüseyin Akşit, İsa Telci, Abdussamat Güzel, Mahfuz Elmastas, Ramazan Erenler. Essential Oil Constituents of Thuja orientalis Berries. Journal of New Results in Science 7 (2014) 1-6.

8. İsmail Çelik, Mehmet Akkurt, Hüseyin Akşit, Ramazan Erenler, Santiago Garcia-Granda. Crystal structure and computational study of 3,4-dihydroxy-3-hydroxymethyl-9-methyl-6-methylidene-3a,4,5,6,6a,9,9a,9b-octahydroazuleno[4,5-b]furan-2,8(3H,7H)-dione. Acta Cryst. (2015). E71, 1425–1428.  Thomson Reuters Emerging Sources Citation Index (ESCI).

9. Ali Aydın, Ramazan Erenler, Bulent Yılmaz, Şaban Tekin. Antiproliferative effect of Cherry laurel. Journal of the Turkish Chemical Society. JOTCSA 3(3), 217-228. 2016.

10. Tunay Karan, Ramazan Erenler, Zekeriya Altuner, Mahfuz Elmastas. Molecular Identification and Norharmane Quantification of Cyanobacterium, Geitlerinema carotinosum. International Journal of Pharmacy and Pharmaceutical Research. Ijppr.Human, 2017; Vol. 9 (3): 66-73.

11. Tunay Karan, Ramazan Erenler, Zekeriya Altuner. Isolation and Molecular Identification of Some Blue-Green Algae (Cyanobacteria) from Freshwater Sites in Tokat Province of Turkey. Turkish Journal of Agriculture - Food Science and Technology, 5(11): 1371-1378, 2017.

12. Ramazan Erenler, Tugba Adak, Tunay Karan, Mahfuz Elmastas, Ilyas Yildiz, Huseyin Aksit, Gulacti Topcu, Murat Aydin Sanda. Chemical Constituents Isolated From Origanum Solymicum With Antioxidant Activitites. The Eurasia Proceedings of Science, Technology, Engineering & Mathematics (EPSTEM). Volume 1, Pages 139-145. 2017.

13. Tunay Karan, Zekeriya Altuner, Ramazan Erenler. Growth and Metabolite Production of Chroococcus minutus Under Different Temperature and Light Conditions. 

JOURNAL OF NEW RESULTS IN SCIENCE (JNRS).  Volume: 6 Issue: 1 Year: 2017 Pages: 47-52.

14.  Ramazan ERENLER, Ibrahim DEMIRTAS, Tunay KARAN, Muhammed ALTUN, Fatih GUL. Inhibitory Effect of 6,7-dimethoxy-5-hydroxyflavone on Human Cervix Carcinoma in Vitro. Int. J. Sec. Metabolite, Vol. 4: 3 (2017) pp. 512-516

15. Tunay KARAN, Omer KAYIR, Zekeriya ALTUNER, Ramazan ERENLER. Growth and norharmane production of Chroococcus minutus under various stress conditions. Int. J. Chem. Technol. 2018, 1, 10-15.

16. Tunay Karan, Seyda Simsek, Ilyas Yildiz, Ramazan Erenler. Chemical Composition and Insecticidal Activity of Origanum syriacum L. Essential Oil Against Sitophilus oryzae and Rhyzopertha dominica. International Journal of Secondary Metabolite 2018, Vol. 5, No. 2, 87–93.

17. İsmail Çelik, Zeliha Atioğlu, Huseyin Aksit, Ibrahim Demirtas, Ramazan Erenler, Mehmet Akkurt. Crystal structure and Hirshfeld surface analysis of 2-oxo-13-epi-manoyl oxide isolated from Sideritis perfoliata. Acta Crystallographica Section E: Crystallographic Communications. 2018. Cilt, 74, Sayı: 5, Sayfalar: 713-717

Research Interest: Topics in chemical quality control in pharmacy practice; Application of different analytical techniques for the determination of pharmaceuticals in the presence of their degradation product(s) including; Different spectrophotometric methods such as colorimetry, derivative and derivative-ratio spectrophotometry. Different chromatographic methods such as TLC-densitometry, Preparative TLC, Two-dimensional TLC, GC and HPLC. Monitoring of the degradation profile of the pharmaceuticals and kinetic studies. Synthesis of the degradation product(s) of the selected drugs and structure elucidation.Chemometric methods, such as CLS, PCR and PLS.

 IR. DR. LAI CHIN WEI is a senior lecturer in the Nanotechnology & Catalysis Research Centre, University of Malaya. He received his Ph.D (2013) from School of Materials and Mineral Resources Engineering, University of Science Malaysia in nanomaterials and nanoscience. Lai’s main research interests are in the areas of chemically modified metal oxide photocatalysts and carbon graphene materials, especially apply in environmental pollution management and solar energy technology. Lai has contributed immensely to the development and enhancement in science & technology in Malaysia, particularly in developing, optimizing and simplifying the technology lies in the synthesis of nanoparticles, metal oxide nano-architecture and carbon/graphene materials which are of high significance for green energy and environment applications. Lai’s works have been published in more than 120 refereed international top-tier journals with h-index of 18 and 100 international proceedings in materials science, physics, chemistry, and renewable energy researches. In all, Lai has reviewed more than 200 papers in the past few years, mainly for top international journals and conferences. Since 2013, his research has been funded by the Ministry of Higher Education of Malaysia, MOHE (FRGS, HIR-MOHE); Ministry of Science, Technology and Innovation of Malaysia, MOSTI (E-Science fund, National Nanotechnology Development), and internal University funding (University of Malaya Research Grant). Being a reputable researcher, his enthusiasm and dedication towards research work, Lai has won several prestigious university, national and international awards in exposition on research innovation, invention & solution. In addition, he successfully awarded “Certificate of Excellent Service UM” for his excellent contribution and service in the year of 2013, 2014 and 2015. Through his work nanomaterials and catalysis field, Lai was awarded the University of Malaya Excellence Awards in the category of outstanding researcher- UM Young Researcher (Sciences Discipline) and selected to be a member of the Young Scientist Network – Academy of Sciences Malaysia (YSN-ASM) in 2015. Lately, Lai was awarded as Finalists National Young Scientist Award 2018 by Ministry of Science, Technology and Innovation of Malaysia and won Mass Young Researcher Award 2018 by Malaysian Solid State Science & Technology Society, Malaysia. On professional qualifications, Lai registered as a Professional Engineer (PEng) in Material Engineering discipline with the Board of Engineers, Malaysia (BEM) and registered as a Chartered Engineer (CEng) with the Engineering Council, UK in 2017. Lai is an active member in The Institution of Engineers, Malaysia (IEM, MAL), Energy Institute (EI, UK) and Institution of Mechanical Engineers (IMechE, UK). He is recognised as among the calibre and outstanding young scientists in the country who have the potential of advancing the scientific ecosystem in Malaysia.

Research Interest: 

Coal Energy Technology (Graphene-based catalysts; Cellulose; Carbon-based catalysts; Carbon nanotubes) Semiconductor Materials (Titanium Dioxide, Tungsten Trioxide, Zinc Oxide, Copper Oxide, Iron Oxide) Nano Materials (Nano-tubes, Nano-rods, Nano-particles, Nano-wires) Solar Energy Technology (Hydrogen Fuel Cell, Photoelectrochemical Cell, Photovoltaic Cell, Dye-Sensitized Solar Cell) Waste Management (Environmental Pollution Management) Composite Materials (Photocatalyst, Metal Oxides, Hybrid Materials, Advanced Materials)

URL: https://scholar.google.com/citations?user=cJf5GyMAAAAJ&hl=en

List of Publications: 

1.    Foo Wah Low, Chin Wei Lai, Christelle Pau Ping Wong, Carbonaceous Composite Materials: Chapter 1: Graphene and Graphene/TiO2 Nanocomposites for Renewable Dye Sensitized Solar Cells, Book ISBN: 9781945291975-1, Publisher: Materials Research Forum LLC, USA [DOI: 10.21741/9781945291975-1].

2.    Chin Wei Lai, Kian Mun Lee, Bey Fen Leo, Christelle Pau Ping Wong and Soon Weng Chong, Polymeric Materials for Clean Water: Chapter 7: Polymers as Water Disinfectants, Book ISBN: 978-3-030-00742-3, Publisher: Springer Nature Switzerland AG. [DOI: 10.1007/978-3-030-00743-0_7].

3.    Swe Jyan Teh, Tong Ling Tan, Chin Wei Lai and Kian Mun Lee, (2018), Carbon Nanotubes for Clean Water: Chapter 5: Catalysis, Book ISBN: 978-3-319-95602-2, Publisher: Springer International Publishing AG, part of Springer Nature. [DOI: 10.1007/978-3-319-95603-9_5]. 

4.    Swe Jyan Teh, Chin Wei Lai, (2018), Applications of Nanocomposite Materials in Dentistry: Chapter 5: Carbon nanotubes for dental implants, Book ISBN 978-0128137420 , Publisher: Woodhead Publishing Elsevier; 1 edition, Oxford, UK, [DOI: 10.1016/B978-0-12-813742-0.00005-5].

5.    Chin Fei Chee, Bey Fen Leo, Chin Wei Lai, (2018), Applications of Nanocomposite Materials in Drug Delivery: Chapter 37: Superparamagnetic nanoparticles for drug delivery, Book ISBN 978-0128137413, Publisher: Woodhead Publishing Elsevier; 1 edition, Oxford, UK, [DOI: 10.1016/B978-0-12-813741-3.00038-8].

6.    Nur Azimah Abd Samad, Kung Shiuh Lau, Chin Wei Lai, (2018), Innovations in Engineered Porous Materials for Energy Generation and Storage Applications: Chapter 11: Wide Band Gap Nano-Semiconductors For Solar Driven Hydrogen Generation, Book ISBN: 978-1-13-873902-4, Publisher: CRC Press/Taylor & Francis Group, The USA.

7.    Christelle Pau Ping Wong, Chin Wei Lai, Joon Ching Juan, (2018), Electrochemical Capacitors: Theory, Materials and Applications; Chapter 7: Hydrothermal Synthesis of Supercapacitors Electrode Materials, Book ISBN 978-1-945291-56-2, Publisher: Materials Research Forum LLC, The USA. [DOI: 10.21741/9781945291579].

8.    Chin Wei Lai, (2018), Nano Hybrids and Composites Vol. 20: Chapter 1: WO3-TiO2 Nanocomposite and its Applications: A Review, Book ISBN 978-3-0357-1256-8, Publisher:Trans Tech Publications Inc.,Switzerland. [DOI: 10.4028/www.scientific.net/NHC.20]

9.    Chin Wei Lai, Kian Mun Lee, Joon Ching Juan, (2017), Nanocomposites for Visible Light-Induced Photocatalysis; Chapter 7: Polymeric Nanocomposites for Visible Light-Induced Photocatalysis, Book ISBN 978-3-319-62446-4, Publisher: Springer International Publishing, UK. [DOI: 10.1007/978-3-319-62446-4].

10.    Izazi Azzahidah Amin, Joon Ching Juan, Chin Wei Lai, (2017), Organic-Inorganic Composite Polymer Electrolyte Membranes: Chapter 12: An Overview of Chemical and Mechanical Stabilities of Polymer Electrolytes Membrane, pp. 327-340, Book ISBN: 978-3-319-52738-3, Publisher: Springer International Publishing, UK. [DOI: 10.1007/978-3-319-52739-0-12].

11.    Chin Wei Lai, Sharifah Bee Abd. Hamid, (2016), Renewable Energy and Sustainable Developments: Chapter 8: A mini review on titanium dioxide photocatalyst: nano-crystalline and nano-tubular systems in solar-driven water electrolysis application, pp. 291-311, ISBN: 978-1-938681-70-7; Publisher: Scientific & Academic P Publishing, USA.

12.    Chin Wei Lai, Kung Shiuh Lau, An Advanced Hybrid Nanocomposite Film and Its Photocatalytic Water Electrolysis Response, International Journal of Nanoelectronics and Materials, Accepted, (2018). (SCOPUS-Indexed)

13.    Foo Wah Low, Chin Wei Lai, Reduced graphene oxide decorated TiO2 for improving dye-sensitized solar cells (DSSCs), Current Nanoscience, Accepted, (2018), DOI: 10.2174/1573413714666180724113106. (ISI-Indexed)

14.    Chin Wei Lai, Kung Shiuh Lau, Pui May Chou, Controlled synthesis of well-aligned and highly ordered TiO2 nanotubes without bundling for enhanced solar-powered photoelectrochemical responses, Journal of Nanoscience and Nanotechnology, Accepted, (2018). (ISI-Indexed)

15.    Chin Wei Lai, Kung Shiuh Lau, Pui May Chou, CdSe/TiO2 Nanotubes for enhanced photoelectrochemical activity under solar illumination: Influence of soaking time in CdSe bath solution, Chemical Physics Letters, Accepted, (2018). DOI: 10.1016/j.cplett.2018.10.054 (ISI-Indexed)

16.    Xin Hui Yau, Cheng Seong Khe, Mohamed Shuaib Mohamed Saheed, Chin Wei Lai, Effect on the Formation of Magnetite Reduced Graphene Oxide with Controlled Stirring Duration, MATEC Web of Conferences, 202, Article Number: 01003, (2018). (SCOPUS-Indexed)

17.    Tong Ling Tan, Chin Wei Lai, Sok Lai Hong, Suraya Abdul Rashid, New insights into the photocatalytic endocrine disruptors dimethyl phathalate esters degradation by UV/MWCNTs-TiO2 nanocomposites, Journal of Photochemistry and Photobiology A: Chemistry, 364, pp. 177-189, (2018). (ISI-Indexed)

18.    Syazwan Hanani Meriam Suhaimy, Chin Wei Lai, Hairul Anuar Tajuddin, Emy Marlina Samsudin, Mohd Rafie Johan, Impact of TiO2 nanotubes’ morphology on the photocatalytic degradation of simazine pollutant, Materials, 11, pp. 2066-2081, (2018). (ISI-Indexed)

19.    Ru Bin Lee, Joon Ching Juan, Chin Wei Lai, Kian Mun Lee, The relationship between iron and Ilmenite for photocatalyst degradation. Advanced Powder Technology, 29(8), pp. 1779-1786, (2018). (ISI-Indexed)

20.    Bao Lee Phoon, Chin Wei Lai, Guan-Ting Pan, Thomas C.-K. Yang, Joon Ching Juan, One-pot hydrothermal synthesis of strontium titanate nanoparticles photoelectrode using electrophoretic deposition for enhancing photoelectrochemical water splitting, Ceramics International, 44(8), pp. 9923-9933, (2018). (ISI-Indexed)

21.    Kian Mun Lee, Chin Wei Lai, Joon Ching Juan, Stability of custom-designed photoreactor for photocatalytic degradation of reactive black 5 dye using zinc oxide, Corrosion Engineering, Science and Technology, 53(7), pp. 462-467, (2018). (ISI-Indexed)

Research Interest: Ischemic Stroke, Diabetic Foot, Anderson-Fabry Disease, Congestive Heart Failure.

Hamed received his PhD in mechanical engineering on a collaborative project between the University of Limerick, Imperial College London and Helmholtz-Zentrüm Berlin, titled "Effect of prior deformation on creep behaviour of AISI 316H austenitic stainless steels" funded by Science Foundation Ireland and EDF (formerly British Energy Ltd.).

He worked at the Irish Centre for Composites Research as lecturer in Finite Element Analysis and Aircraft Structures, and as a post-doctoral researcher on three consecutive industrial-oriented projects on composites materials, MAAXIMUS project funded through EU FP7 grant agreement nº213371 led by Airbus (www.maaximus.eu), Design of Optimised Composites for Impact Applications (OPTCOM) project funded by Enterprise Ireland (grant CF/2013/3012B), and the Science Foundation Ireland funded FALCOM project (www.falcom.ie) on a novel adhesively bonded joining technology.

Research Interest: 

•    Airworthiness

•    Composites

•    Computing, Simulation & Modelling

•    Manufacturing of Functional Materials

•    Aerospace Materials

•    Nanomaterials

•    Renewable Energy

•    Smart Materials

•    Structures and Materials

URL: https://www.cranfield.ac.uk/people/dr-hamed-yazdani-nezhad-14085695

List of Publications: 

1.    Deane, S, Avdelidis HP, Ibarra-Castanedo C, Zhang H, Yazdani Nezhad H, Williamson AA, Mackley T, Davis MJ, Maldague X & Tsourdos A (2019) Application of NDT thermographic imaging of aerospace structures, Infrared Physics and Technology, 97 (March) 456-466.
2.    Liu Y, Zhang X, Lemanski S, Yazdani Nezhad H & Ayre D (2019) Experimental and numerical study of process-induced defects and their effect on fatigue debonding in composite joints, International Journal of Fatigue, 125 (August) 47-57.
3.    Sirikham A, Zhao Y, Yazdani Nezhad H, Du W & Roy R (2019) Estimation of damage thickness in fiber-reinforced composites using pulsed thermography, IEEE Transactions on Industrial Informatics, 15 (1) Article No. TII-18-2286 445-453.
4.    Yazdani Nezhad H,Stratakis D, Ayre D, Addepalli S & Zhao Y (2018) Mechanical performance of composite bonded joints in the presence of localised process-induced zero-thickness defects, Procedia Manufacturing, 16 91-98.
5.    Lotfian S, Giraudmaillet C, Yoosefinejad A, Thakur VJ & Yazdani Nezhad H (2018) Electrospun piezoelectric polymer nanofiber layers for enabling in situ measurement in high-performance composite laminates, ACS Omega, 3 (8) 8891-8902.
6.    Mgbemena CO, Li D, Lin MF, Liddel PD, Katnam KB, Kumar VT & Yazdani Nezhad H (2018) Accelerated microwave curing of fibre-reinforced thermoset polymer composites for structural applications: A review of scientific challenges, Composites Part A: Applied Science and Manufacturing, 115 (December) 88-103.
7.    Yazdani Nezhad H & Thakur VJ (2018) Effect of morphological changes due to increasing carbon nanoparticles content on the quasi-static mechanical response of epoxy resin, Polymers, 10 (10) Article No. 1106.
8.    Liu Y, Lemanski S, Zhang X, Ayre D & Yazdani Nezhad H (2018) A finite element study of fatigue crack propagation in single lap bonded joint with process-induced disbond, International Journal of Adhesion and Adhesives, Early online.
9.    Yazdani Nezhad H, Egan B, Merwick F & McCarthy CT (2017) Bearing damage characteristics of fibre-reinforced countersunk composite bolted joints subjected to quasi-static shear loading, Composite Structures, 166 (April) 184-192.
10.    Bhanushali R, Ayre D & Yazdani Nezhad H (2017) Tensile response of adhesively bonded composite-to-composite single-lap joints in the presence of bond deficiency, Procedia CIRP, 59 139-143.
11.    Yazdani Nezhad H, Zhao Y, Liddel PD, Marchante VR & Roy R (2017) A novel process-linked assembly failure model for adhesively bonded composite structures, CIRP Annals - Manufacturing Technology, 66 (1) 29-32. Dataset/s: 10.17862/cranfield.rd.4681009
12.    Yazdani Nezhad H & O'Dowd N (2015) Creep relaxation in the presence of residual stress, Engineering Fracture Mechanics, 138 250-264.
13.    Zhou Y, Yazdani Nezhad H, Hou C, Wan X, McCarthy C & McCarthy M (2015) A three dimensional implicit finite element damage model and its application to single-lap multi-bolt composite joints with variable clearance, Composite Structures, 131 1060-1072.
14.    Yazdani Nezhad H, Merwick F, Frizzell R & McCarthy C (2014) Numerical analysis of low-velocity rigid-body impact response of composite panels, International Journal of Crashworthiness, 20 (1) 27-43.
15.    Zhou Y, Yazdani-Nezhad H, McCarthy M, Wan X & McCarthy C (2014) A study of intra-laminar damage in double-lap, multi-bolt, composite joints with variable clearance using continuum damage mechanics, Composite Structures, 116 441-452.
16.    Yazdani Nezhad H & O'Dowd NP (2012) Study of creep relaxation under combined mechanical and residual stresses, Engineering Fracture Mechanics, 93 132-152.

2017-Postdoctoral researcher

Gaziosmanpasa University, Turkey Plant Research Lab of Chemistry, Faculty of Arts and Sciences

2011-2016 PhD (Research Assis-tant) Gaziosmanpasa University Molecular Biology and Genetics, Faculty of Arts and Sciences

2008- 2011 Master (Research Assis-tant) Gaziosmanpasa University Molecular Biology and Genetics, Faculty of Arts and Sciences

2003-2007 Under graduate Cumhuriyet Univer-sity Biology, Faculty of Arts and Sciences

Research Interest:  Algae cultivation, Plant biotechnology, Secondary metabolite production

Grants: 

1. Bioprocessingof microalgae for production and recovery of high-value metabolites;", Texas A&M University, 23.08.2015 -29.11.2015

2. Activity Controlled Isolation of Isolated Secondary Metabolites from Cladophora fracta (Tubitak 2017-2018).

3. Investigation of Pharmacological Secondary Metabolites in Some Cyanobacteria Members and Investigation of the Effects of Various Stress Conditions on the Production of these Metabolites (2016- 2018 Bap Turkey).

List of Publications: 

1. Tunay Karan, Ramazan Erenler Zekeriya Altuner, Mahfuz Elmastas. Molecular Identification and Norharmane Quantification of Cyanobacterium, Geitlerinema carotinosum. International Journal of Pharmacy& Pharmaceutical Research.June 2017,  Vol.:9, Issue:3, 67-73.

2. Tunay Karan, Ramazan Erenler. Screening of Norharmane from Seven Cyanobacteria by High performance Liquid Chromatography. Pharmacogn. Mag. 11.10.2017, Vol: 13, Issue: 51, 723-725.

3.Tunay Karan, Zekeriya Altuner, Ramazan Erenler. Growth and Metabolite Production of Chroococcus minutus Under Different Temperature and Light Conditions. Journal of New Results in Science, 6:1 47-52, 2017.

4. Tunay KARAN, Taner DAŞTAN, İnanç BARAL, Zekeriya ALTUNER.   Effects of Differential Time Applications on Some Cyanobacterial Norharman Production Rates.  Cumhuriyet Üniversitesi Fen Fakültesi Fen Bilimleri Dergisi (CFD), Cilt 37, No. 4 (2016) ISSN: 1300-1949.

5. Tunay KARAN, Ramazan ERENLER, Zekeriya ALTUNER. Isolation and Molecular Identification of Some Blue-Green Algae (Cyanobacteria) from Freshwater Sites in Tokat Province of Turkey. Turkish Journal of Agriculture - Food Science and Technology, 5(11): 1371-1378, 2017

6.Tunay KARAN, Saban Tekin, Ahmet Bursalı, Adem Keskin. Investigation of Tick-Borne Encephalitis Virus (TBEV) in Ixodid Ticks  Collected from Central Black Sea Region in Turkey. Journal of New Results in Science 4 (2014) 30-35

7.Sevgi Durna Dastan, Naci Degerli, Taner Dastan, Fazilet Yildiz, Yavuz Yildir, Yusuf Muhammed Durna, Dilek Atessahin  and Tunay Karan. Phenylthiocarbamide taste perception as a possible genetic association marker for nutritional habits and obesity tendency of people. Pak. J. Pharm. Sci., Vol.28, No.3(Suppl), May 2015, pp.1141-1150. 

8. Sevgi Durna Daştan, Taner Daştan, Serap Çetinkaya, Dilek Ateşşahin, Tünay Karan. Evaluation of In Vitro Anticancer Effect of Plantago major L. and Plantago lanceolata L. Leaf Extracts from Sivas. Cumhuriyet Üniv. Sağ. Bil. Enst. Derg. 2016 (1)1: 07-14

9. Tunay KARAN, İlyas Yıldız, Ali Aydın, ,Ramazn Erenler Inhibition of Various Cancer Cells Proliferation of Bornyl Acetate and Essential Oil from Inula graveolens (Linnaeus) Desf.  Rec. Nat. Prod. 12:3 (2018) 273-283

10. Ramazan Erenler, Tuğba Adak, Tunay KARAN, Mahfuz Elmastaş,İlyas Yıldız, Hüseyin Akşit,Gülaçtı Topcu,Murat Aydın Sanda. CHEMICAL CONSTITUENTS ISOLATED FROM ORİGANUM SOLYMICUM WITH ANTIOXIDANT ACTIVITITES. The Eurasia Proceedings of Science, Technology, Engineering & Mathematics (EPSTEM)  2017,Volume 1, Pages 139-145

11. Tünay KARAN, Mesut KOYUNCU, İskender PARMAKSIZ, Köksal PABUÇCU, Zekeriya ALTUNER. Siyanotoksinler ve Biyosentezlerinden Sorumlu Genlerin Düzenlenmesi. Gaziosmanpaşa Fen Bilimeri Enstitüsü Bilimsel Araştırma Dergisi 11 (2015) 54-69 .

12. KARAN TÜNAY,TEKIN SABAN, BURSALI AHMET.‘Crimean-Congo Hemorrhagic Fever Virus in Ixodid Ticks in Tokat Province of Turkey. Abstracts / Journal of Biotechnology 161S (2012) 19–48. 

13. Tunay KARAN, Saban Tekin, Adem Keskin, Ahmet Bursalı. Testing The Presence of Tick-Borne Encephalitis Virus in Ixodid Ticks (Acari: Ixodidae) From Tokat and Ordu Vicinity. In vivo International Journal of Experimental and Clinical Pathophysiology and Drug Research. 25:3 467-576 (2011).

14. Tunay KARAN, Omer KAYIR, Zekeriya ALTUNER, Ramazan ERENLER.Growth and norharmane production of Chroococcus minutus under various stress conditions.2018, 1, 10-15.

15.Tunay KARAN.  Metabolic profile and biological activities of Lavandula stoechas L. Cellular and Molecular Biology E-ISSN : 1165-158X / P-ISSN : 0145-5680.

16. Tunay Karan, Ramazan Erenler. Fatty acid constituents and anticancer activity of Cladophora fracta (OF Müller ex Vahl) Kützing. Tropical Journal of Pharmaceutical Research October 2018; 17 (10): 1977-1982.

17. Tunay Karan, Ali Aydin. Anticancer potential and cytotoxic effect of some freshwater cyanobacteria. Tropical Journal of Pharmaceutical Research November 2018; 17 (11): 2183-2188.

18.Evanthia Mantzouki, Tunay KARAN and et. al. Temperature Effects Explain Continental Scale Distribution of Cyanobacterial Toxins. Toxins 2018, 10, 156.

19.Evanthia Mantzouki, Tunay KARAN and et. al. A European Multi Lake Survey dataset of

environmental variables, phytoplankton pigments and cyanotoxins. Scıentıfıc Data 5:180226 DOI: 10.1038/sdata.2018.226.

20. Tunay Karan and Bilge Hilal Cadirci. Evaluatıon of antımıcrobıal and antıoxıdant actıvıty of lepıdıum draba l. World Journal of Pharmaceutical Research, Vol 7, Issue 13, 2018.

Research Interest: Medicinal Chemistry; Peptidomimetics;  Enzyme Inhibitors;  Negleted Tropical Diseases; Cysteine Protease; Rhodesain; Falcipain-2; Antitumor Agents; Proteasome.

Research Interest: Natural Product Chemistry, Medicinal Chemistry, Chemical Biolgoy

Research Interest: Synthesis of novel heterocycles as anticancer agents; Computer Aided Drug Design.